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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Androgens slow hair growth by altering Wnt signaling in balding cells.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Tamoxifen effectively treats gynecomastia without causing impotence.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Sex hormones affect brain injury differently in males and females.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

Finasteride helps protect brain in old male rats.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Finasteride affects young male rats' brain function and behavior negatively.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

Higher DHT in male baldness may protect against prostate cancer.

A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.

Policosanol helps treat hair loss by balancing hormones and supporting hair growth.