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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Eating a lot of soy might lower the chance of early hair loss in men likely to get it.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Melatonin may help treat PCOS symptoms in rats.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Thymosin β4 helps improve skin healing and reduce scarring.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

CD4+ skin cells may be precursors to basal cell carcinoma.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.