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Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

The Hairless gene is crucial for healthy skin and hair growth.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Estrogen and prolactin may play bigger roles in female hair loss than previously thought.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Estrogen helps keep skin healthy and may make women look younger and more attractive.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sex hormones affect brain injury differently in males and females.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.