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      COVID-19 and Sex Differences: Mechanisms and Biomarkers

      research COVID-19 and Sex Differences

      185 citations , August 2020 in “Mayo Clinic Proceedings”
      This review discusses biological sex differences in COVID-19 outcomes and reports no new clinical results; it identifies a need for studies to clarify how sex influences disease progression.
      Skin Aging and Menopause: Implications for Treatment

      research Skin Aging and Menopause

      180 citations , January 2003 in “American Journal of Clinical Dermatology”
      This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
      Summary of the Recommendations on Sexual Dysfunctions in Women

      research Summary of the Recommendations on Sexual Dysfunctions in Women

      177 citations , July 2004 in “The Journal of Sexual Medicine”
      This review provides updated guidelines for diagnosing and managing women's sexual dysfunctions but reports no new clinical findings; it emphasizes the need for ongoing research and long-term outcome studies.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      Gender Differences in Skin: A Review of the Literature

      research Gender differences in skin: A review of the literature

      152 citations , December 2007 in “Gender Medicine”
      This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.

      research Localization of sex steroid receptors in human skin.

      147 citations , April 2004 in “PubMed”
      This study identifies specific localization patterns of androgen, estrogen, and progesterone receptors in human skin, which could be crucial for understanding their roles in skin biology and pathology.
      Hormone Therapy for Transgender Patients

      research Hormone therapy for transgender patients

      146 citations , December 2016 in “Translational Andrology and Urology”
      This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
      Hormone Replacement Therapy and the Skin

      research Hormone replacement therapy and the skin

      138 citations , May 2000 in “Maturitas”
      This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.
      Clinical Management of Youth with Gender Dysphoria in Vancouver

      research Clinical Management of Youth with Gender Dysphoria in Vancouver

      116 citations , December 2013 in “The Journal of Pediatrics”
      This study reported that treatment with gonadotropin-releasing hormone analogs and cross-sex hormones appears appropriate for carefully selected youth with gender dysphoria, but long-term safety needs further investigation.
      Melatonin and the Hair Follicle

      research Melatonin and the hair follicle

      109 citations , October 2007 in “Journal of pineal research”
      This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.

      research Steroid sulfatase inhibitors

      108 citations , April 2004 in “Medicinal Research Reviews”
      This review discusses the medicinal chemistry of steroid sulfatase inhibitors for estrogen- and androgen-dependent disorders but reports no new clinical results.

      research Hormonal Effects on Hair Follicles

      102 citations , July 2020 in “International journal of molecular sciences”
      This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.
      Endocrine Aspects of Female Sexual Dysfunction

      research Endocrine Aspects of Female Sexual Dysfunction

      100 citations , July 2004 in “The Journal of Sexual Medicine”
      This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.
      Endocrine Control of Benign Prostatic Hyperplasia

      research Endocrine control of benign prostatic hyperplasia

      97 citations , April 2016 in “Andrology”
      This review discusses the etio-pathogenetic factors in benign prostatic hyperplasia and their role in the development of lower urinary tract symptoms but reports no new research findings.
      Current Evaluation of Amenorrhea

      research Current evaluation of amenorrhea

      78 citations , November 2008 in “Fertility and Sterility”
      Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
      Skin Connective Tissue and Aging

      research Skin connective tissue and ageing

      77 citations , July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.

      research Sex hormones and acne

      76 citations , October 2016 in “Clinics in dermatology”
      This review discusses the hormonal and genetic factors influencing acne development, emphasizing the role of androgens and insulin signaling but reports no new clinical results.
      Skin Aging

      research Skin ageing

      76 citations , May 2007 in “Menopause International”
      This review discusses the relationship between estrogen deficiency and skin aging in postmenopausal women, noting potential benefits of estrogen use on skin collagen and elasticity, but reports no new clinical results.
      Physiological and Biological Skin Changes in Pregnancy

      research Physiological and biological skin changes in pregnancy

      71 citations , February 2006 in “Clinics in Dermatology”
      This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.
      Causes of Hair Loss and Developments in Hair Rejuvenation

      research Causes of hair loss and the developments in hair rejuvenation

      69 citations , February 2002 in “International Journal of Cosmetic Science”
      This review discusses genetic and nutritional causes of hair loss, highlighting that around 90% of treated men show noticeable hair regrowth with a dual inhibitor, while women's hair loss may improve by correcting iron and l-lysine deficiencies.
      Male Gonadal Function in Coeliac Disease: Sex Hormones

      research Male gonadal function in coeliac disease: 2. Sex hormones.

      69 citations , February 1983 in “Gut”
      This study found that untreated men with coeliac disease exhibited androgen resistance, potentially linked to sexual dysfunction, which improved as intestinal health improved, a pattern not observed in other chronic illnesses.