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Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Women also use 5α-reductase inhibitors, and their effects differ from men.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Women also use 5α-reductase inhibitors for hair loss and hirsutism.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Mouse genital development depends on male or female hormones for specific features.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.