Women Also Use 5α-Reductase Inhibitors

The document highlighted the importance of including sex-specific language in research titles, particularly in studies involving hormonal manipulations. It noted that 5α-reductase inhibitors, which are approved for treating hirsutism and alopecia in women, can lead to increased estrogen levels. The metabolic consequences of male hypogonadism and female hyperandrogenism were found to be strikingly similar, but the endocrine, metabolic, vascular, and psychological responses to testosterone inhibition differ between men and women. The document emphasized the need for sex-specific research findings and the importance of conducting studies in both sexes whenever possible.