Women Also Use 5α-Reductase Inhibitors

    November 2017 in “ JAMA internal medicine ”
    Siddika E Karakas
    TLDR Women also use 5α-reductase inhibitors for hair loss and hirsutism.
    The document highlighted the importance of including sex-specific language in research titles, particularly in studies involving hormonal manipulations. It noted that 5α-reductase inhibitors, which are approved for treating hirsutism and alopecia in women, can lead to increased estrogen levels. The metabolic consequences of male hypogonadism and female hyperandrogenism were found to be strikingly similar, but the endocrine, metabolic, vascular, and psychological responses to testosterone inhibition differ between men and women. The document emphasized the need for sex-specific research findings and the importance of conducting studies in both sexes whenever possible.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 181 results

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community We are manipulating our hormones, surely it's prudent to track bloodwork ?

      in Finasteride/Dutasteride  64 upvotes 1 year ago
      The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

      community Andrew Schulz stated he had been using a ‘’hair pill’’ for 15 years and it may have caused him infertility

      in Satire  134 upvotes 2 years ago
      The conversation discusses the potential link between hair loss treatment pills, specifically finasteride, and infertility. Users share their experiences and opinions, with some suggesting that finasteride can temporarily lower sperm count, while others argue that other factors like age and lifestyle could also contribute to infertility.

      community Why does it seem everyone favors finasteride over dutasteride?

      in Female  62 upvotes 1 year ago
      The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  210 upvotes 1 year ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community Is anyone using melatonin for hair loss?

      in Research/Science  9 upvotes 1 year ago
      Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

    Similar Research

    5 / 1000+ results