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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male pattern baldness involves genetics, hormones, and needs better treatments.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

2% topical minoxidil effectively treats female hair loss with minimal side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

A new gene, JMJD1C, may affect testosterone levels in men.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.