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This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.

This study identified the structures of cyclohexyl and phenyl analog impurities in finasteride using HPLC and spectral analysis.

This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.

This study identified novel selective androgen receptor modulators with enhanced in vivo pharmacological activity through structure-activity relationship analysis in castrated rats.

This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.

This study found that a combined oral contraceptive containing ethinyl estradiol and desogestrel appeared effective in temporarily treating ovarian hyperandrogenism in adolescents, with reductions in hormone levels and ovarian volume observed.

This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.

This study found that a synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), can coat gray hair and gradually oxidize, creating a resistant brown layer similar to apple browning, which offers a practical hair dyeing solution that withstands washing and reduces the need for long dyeing sessions.

This chapter reviews various chemical synthesis methods for pharmaceutical compounds and reports no new experimental results.

This study found that peach kernel oil extracted via supercritical fluid extraction had higher quality and antioxidant properties than oil obtained by other methods, effectively protecting human hair follicle keratinocytes from oxidative damage.

This study identified a new compound from fermented Carica papaya L. with moderate antioxidant and potent hair growth-stimulating activities in vitro.

In this laboratory study on rabbits, the researchers observed that both FET and FHE fractions improved hair length and weight, but minoxidil still led to better results, highlighting the comparative effects of different treatments on hair growth over 28 days.

This case study reports that pancreatic enzyme replacement and fatty acid supplementation improved symptoms of fat malabsorption and essential fatty acid deficiency in a patient with EDS-4.

In this study, using tyrosine as a cross-linking agent for hair perming showed better initial results compared to commercial products, though efficiency decreased after washing without compromising hair strength.

This study used NMR spectroscopy and other techniques to fully assign the proton and 13C spectra of the 5α-reductase inhibitor finasteride.

This study used Density Functional Theory to calculate finasteride's molecular properties, finding the GGA/PW91 method aligns well with experimental data and identifying key reactive sites for chemical interactions.

In this study, fluorescence microscopy revealed that a cationic cellulose ether derivative adsorbed onto hair fibers desorbed significantly when treated with sodium dodecylsulfate.

This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.

This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.

This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.

In this study, researchers found that an ethyl acetate extract of the green microalga Scenedesmus deserticola significantly increased the viability of human dermal fibroblasts by over 20% compared to a control and identified a potent anti-UV compound, loliolide, through further fractionation.

This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.

This study found that emodin from Polygonum multiflorum showed 5alpha-reductase inhibitory activity, which was more potent than alizarin but less potent than riboflavin.

This study found that finasteride is stable under various stress conditions except for basic hydrolysis at extreme pH levels and identified compatible and incompatible excipients in pharmaceutical formulations, suggesting formulation changes for increased safety.

This study successfully synthesized novel cercidin analogues from Cercidophyllum japonicum, confirming their structure via NMR data. The researchers suggest these compounds could facilitate future antibiotic development by advancing structure-activity-relationship studies.

This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.

This review explores the complex relationships between ferroptosis, anastasis, and chemoresistance in cancer therapy, highlighting the potential of combining ferroptosis with immunotherapy to overcome resistance and improve personalized cancer treatments.