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This study found that differently charged micelles influence the acid-base equilibria of cetirizine by altering its ionization constants, indicating potential interactions with biomolecules of various charges under physiological conditions.

This study found that the optimal characteristics for ulin seed oil extraction are fresh, mature, and resinous seeds, and that FTIR spectrophotometry with PCA can effectively detect adulteration of the oil, particularly at certain wavenumbers like 1745 cm⁻¹.

This synthesis report details the successful development of a C-14 labeled isotopomer of LY300502, a 5α-reductase inhibitor, through a multi-step radiochemical process.

This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.

This study found that sheep wool follicles actively oxidize acetate and glucose, suggesting the involvement of the TCA cycle for compound synthesis and the potential role of the pentose phosphate pathway in ribose production for RNA and DNA.

This study found that both topical tretinoin and oral isotretinoin altered the free fatty acid profile of sebum in acne patients, affecting bacterial growth differently for S. epidermidis and S. aureus.

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

This review discusses ethosomes as lipid carriers that enhance drug penetration into deep skin layers and underscores the need for advanced research on their pharmaceutical applications, but it reports no clinical outcomes.

This study found that social isolation in rats enhanced ethanol's effects on brain steroidogenesis and GABA A receptor function, altering related behavior more than in non-isolated rats.

This study found that treating permed hair with diethylene glycol monoethylether significantly reduced the formation of split ends, making it similar to untreated normal hair in terms of split ends generation.

This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.

This study observed that both in vitro and in vivo research demonstrated rice bran extract can significantly enhance collagen and elastin synthesis, reduce water loss, and improve skin quality and elasticity, highlighting its potential as a sustainable cosmetic ingredient.

This study investigated the effect of peracetic acid treatment on hair fiber structure and found that disulfide bond oxidation altered thermal properties while preserving the α-crystal structure, suggesting different stabilizing interactions in hair fibers.

This study found that non-toxic polycarboxylic acids can achieve satisfactory hair perming effects with limited strength loss, suggesting they have potential as a safer alternative to harmful perming chemicals.

This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.

This study found that, compared to oxidative treatments, reductive perm-waving more severely impacts the intermediate filaments in European human hair, while both treatments alter denaturation kinetics in a first-order manner.

This case report describes a 62-year-old man with psoriasis who developed a unique nail abnormality after two months of treatment with the oral retinoid etretinate, alongside hair thinning and cheilitis.

This study developed effervescent cleansing tablets containing asiatic-acid-loaded solid lipid microparticles, finding that they provided effective cleansing compared to water and showed good flow properties, pH, and hardness but were unstable at high temperature and humidity.

This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.

This review examines the science and technology behind temporary and permanent hair straightening, discussing the processes, potential advancements, and considerations for reducing adverse effects, but does not report new research findings.

This study found that rebonding hair straightening treatments visibly damage the hair cuticle, causing surface erosion and cracks, as shown through Scanning Electron Microscopy analysis.

This study describes a double embedding technique for preparing tangential sections of hair and wool fibers, recommending specific staining methods for quantitative analysis and demonstrating wool fiber cortical fractions.

This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.

This study found that newly synthesized steroidal trienones demonstrated stronger 5α-reductase inhibitory activity compared to dienones in various biological models, suggesting potential for developing enhanced antiandrogenic drugs.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This paper describes recent advancements in the synthesis of thiasteroids but reports no new experimental results, noting that introducing heteroatoms in steroidal structures has potential biological effects.

This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.

This study found that chemical treatments such as hair bleach and UV radiation significantly reduced the amount of 18-methyleicosanoic acid on the outer surface of human hair.