Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner

November 2014 in “ Behavior Genetics ”

Matthew M. Ford, Jeffrey D. Nickel, Moriah N. Kaufman, Deborah A. Finn

We don't know much about this study yet.

We're maintaining the world's largest resposity of hair loss research. You can help out the community by sending a PDF of this study here . Not sure how to get a study's PDF? You can email the authors of the study.

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research Replacement with GABAergic Steroid Precursors Restores the Acute Ethanol Withdrawal Profile in Adrenalectomy/Gonadectomy Mice

12 citations , December 2009 in “Neuroscience”

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

research Inhibition of 5α-Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice

49 citations , July 2008 in “Alcoholism Clinical and Experimental Research”

research Ethanol Intake Patterns in Female Mice: Influence of Allopregnanolone and the Inhibition of Its Synthesis

35 citations , May 2008 in “Drug and Alcohol Dependence”

research Modulation of Neuropeptide Y and Y1 Receptor Expression in the Amygdala by Fluctuations in the Brain Content of Neuroactive Steroids During Ethanol Drinking Discontinuation in Y1R/LacZ Transgenic Mice

15 citations , November 2007 in “Journal of Neurochemistry”

research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride

137 citations , March 2006 in “Cns Drug Reviews”

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Treatment With and Withdrawal From Finasteride Alter Ethanol Intake Patterns in Male C57BL/6J Mice: Potential Role of Endogenous Neurosteroids

research Treatment With and Withdrawal From Finasteride Alter Ethanol Intake Patterns in Male C57BL/6J Mice: Potential Role of Endogenous Neurosteroids

54 citations , August 2005 in “Alcohol”

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Related Research

2 / 2 results

research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior

18 citations , September 2021 in “Journal of Neuroendocrinology”

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy

23 citations , July 2003 in “Pharmacology, Biochemistry and Behavior”

Finasteride blocks progesterone's effect on absence seizures in rats.