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This study reports that 14 of 19 patients with erythema nodosum leprosum had C3 deposits in vessel walls when examined using direct immunofluorescence.

Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.

This study found that XiaoZhenFang (XZF) reduced skin toxicities caused by Erlotinib in a mouse model, likely through mechanisms involving inflammation and EGFR-related pathways.

A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.

This study reports two cases of PRIDE complex in nonsmall cell lung cancer patients treated with erlotinib and gefitinib, highlighting cutaneous reactions like papulopustules and paronychia.

This study found that ethanolic asiasari radix extract may induce apoptosis in G361 melanoma cells through ROS-dependent regulation of p53, suggesting potential as a medicinal option for melanoma.

In this study, introducing the rat OTC gene into spf-ash mice led to increased OTC activity and normalized hair growth and biochemical markers like urinary orotic acid and serum citrulline, partially correcting the symptoms of OTC deficiency.

In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.

This study identified a mutation in the KRTHB6 gene in two monilethrix families of Indian origin, linking specific genetic variations to different severities of hair defects within the families.

This study found that the transcription factor CAP1 negatively regulates KRT83 expression in Tan sheep, possibly influencing their curly hair phenotype.

The method produces finasteride with a 92% yield.

This study provided the first X-ray crystal structure of the mammalian steroid hormone reductase AKR1D1 and identified a disease-related mutant, P133R, which may impact bile acid metabolism and cause clinical symptoms.

This study found that human hair keratin scaffold material implanted in damaged rabbit muscle tissue degrades via the ubiquitin system and is further processed by macrophagocytes and lysosomes.

In this study, EREG promoted hair growth by activating specific receptors in cell and animal models, indicating it may be a potential treatment for hair loss.

Among a Han Chinese cohort, this study found that a higher genetic risk score was linked to increased susceptibility to BPH, larger prostate size, reduced effectiveness of 5ARI treatment, and a higher risk of undergoing TURP.

This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.

This review discusses the clinical manifestations and immune response to Rhodococcus equi infection in foals but reports no new clinical results.

In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.

This study suggests that impaired Nrf2 signaling and its relationship with keratin 16 may contribute to follicular hyperkeratinization and occlusion in hidradenitis suppurativa, opening new therapeutic avenues.

This study suggests that monitoring CD8+ TEMRA cells in patients with rapidly progressive alopecia areata treated with intravenous corticosteroids could help predict therapeutic outcomes.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

This article reports on a Consent Agreement by the New York State Board charging Dr. Dennis Daly with professional misconduct related to unqualified and unlicensed practice.

This study found that ureteroileal anastomosis with direct intraluminal visualization had a 4.2% stricture rate, which compares favorably to other techniques with rates between 3.5% and 11.1%.

This study found that nuclear androgen receptors are not necessary for androgen self-administration, suggesting that plasma membrane receptors might be involved.

This study suggests that residues Val-889 and Arg-752 in the androgen receptor's steroid binding domain are crucial for NH2-/carboxyl-terminal interaction, affecting receptor stability and function.

This study found that phenylbutazone and fluocinolone acetonide have similar anti-redness effects in both haired and hairless animals, making hairless rats a potential alternative for testing without needing depilation.

This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, with effects comparable to metformin.