29 citations,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
14 citations,
March 2022 in “Clinical Endocrinology” The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).
9 citations,
March 2022 in “Journal of the Endocrine Society” Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.
7 citations,
December 2019 in “Pharmaceutics” Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
6 citations,
August 2023 in “Fertility and Sterility” The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
6 citations,
August 2023 in “European journal of endocrinology” The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.
4 citations,
January 2023 in “Skin health and disease” Blocking Janus kinase 1 helps stop inflammation and regrow hair, making it a good treatment for hair loss from alopecia areata.
2 citations,
September 2020 Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.
1 citations,
November 2021 in “Ultrasonography” Ultrasound boosts finasteride's hair growth effects in mice.
Melatonin and photobiomodulation are effective for treating Alopecia X in German Spitz dogs.
March 2023 in “Scientific Reports” Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
10 citations,
September 2020 in “Biopolymers” Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.
70 citations,
June 1993 in “Biochemistry” Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
24 citations,
July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
1 citations,
August 2023 in “Cutis” Low ferritin levels can indicate iron deficiency as a cause of hair loss.
1 citations,
November 2015 in “Indian Journal of Clinical Biochemistry” The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
305 citations,
July 2016 in “International Journal of Biological Macromolecules” Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
268 citations,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
155 citations,
August 1991 in “Journal of The American Academy of Dermatology” Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
136 citations,
March 1996 in “Journal of the American Chemical Society” Finasteride effectively blocks enzyme causing male pattern baldness.
85 citations,
January 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
47 citations,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
43 citations,
July 2016 in “European journal of pharmaceutical sciences” Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
35 citations,
June 2005 in “The Milbank Quarterly” The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
27 citations,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
24 citations,
November 1978 in “Biochemistry” α-type filaments in guinea pig hair follicles have unique structural features.
21 citations,
September 1977 in “Journal of Pharmaceutical Sciences” Minoxidil levels measured in human blood.
18 citations,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
13 citations,
July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.