This study found that ethanol and methanol extracts of Spirulina platensis did not exhibit cytotoxic activity on WiDr colon cancer cells.
The levels of zinc, vitamin D, ferritin, and selenium are different in people with androgenic alopecia compared to a control group.
October 2017 in “Doctoral thesis, UCL (University College London).” This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.
January 2017 in “Enlighten: Publications (The University of Glasgow)” This study found that in mice with deregulated β-catenin and PTEN signaling, increased follicular hyperplasia and sebaceous gland changes occur, but typical papillomas do not develop, potentially due to p21 response and reduced stem cell markers.
This study describes various actions taken by parents to manage the side effects of chemotherapy in children with leukemia, highlighting a range of strategies from dietary adjustments to topical treatments.
In this study, mangosteen pericarp extract was found to promote hair dermal papilla cell proliferation and enhance melanin synthesis, suggesting its potential as an ingredient in hair growth and tanning products.
January 2016 in “The Australian Pharmacist” Tofacitinib might be used to treat hair loss.
This study found that both levetiracetam and valproate sodium effectively reduced seizure frequency and duration in patients with refractory epilepsy, but levetiracetam had fewer side effects related to liver enzyme changes.
This study found that young adults, particularly females, experiencing diffuse hair fall had significantly lower Vitamin D3 levels compared to their age-matched healthy counterparts.
November 2014 in “Research Information System of Ardabil University of Medical Sciences (Ardabil University of Medical Sciences)” January 2014 in “UMS Institutional Repository (Universiti Malaysia Sabah)” This study found that Murraya koenigii extracts and compounds demonstrated potent antibacterial and cytotoxic activities, with notable effects against antibiotic-resistant strains and cancer cell lines, supporting its potential for further pharmacological investigation.
August 2013 in “Annals of Translational Medicine” This review discusses human placental extract's potential for regenerating cartilage and reducing inflammation in osteoarthritis, noting promising in vitro and in vivo results but reports no new clinical outcomes.
January 2011 in “Journal of Human Genetics” This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.
December 2010 in “Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University)” This thesis explores both environmental and genetic factors in prostate cancer, focusing on surrogate hormone markers, medical radiation, family history, and genetic polymorphisms related to DNA repair and hormone marker genes, but reports no new clinical findings.
January 2010 in “CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche)” This study found that combining metformin and clomifene citrate improved pregnancy outcomes and reduced miscarriage rates in women with PCOS and infertility undergoing intrauterine insemination.
January 2009 in “Acta urologica Belgica” In this placebo-controlled study, finasteride significantly improved symptoms, reduced prostate size, and increased urine flow rate in patients with moderately symptomatic BPH over two years.
This study identified novel mutations associated with ectodermal dysplasias in Pakistani families, including a missense mutation in the KRTHB5 gene linked to pure hair-nail ectodermal dysplasias and mutations in the EDAR gene related to hypohidrotic ectodermal dysplasia.
EGF and FGF signaling stops hair follicle development in mice.
This study found that low-level laser therapy may effectively stimulate hair growth in adults with androgenic alopecia, but further research is needed to confirm its long-term clinical effectiveness.
January 1999 in “Journal of Investigative Dermatology” This study suggests that the long non-coding RNA Xist is a key factor in sex differences in systemic lupus erythematosus and rheumatoid arthritis, affecting immune cell behavior and inflammatory pathways in women.
This study observed that both 15% topical Minoxidil and low-level laser therapy increased patient satisfaction in treating androgenetic alopecia, but physician satisfaction was higher for Minoxidil, despite it causing more side effects.
This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.
This study found no significant difference in hair outcomes between patients using Minoxidil 1 shampoo and a placebo shampoo for alopecia over four months.
In this study, patients with androgenetic alopecia who underwent hair transplantation reported significant improvements in physical, mental, and social health, as well as decreased anxiety and depression scores.
January 2013 in “Faculty of Health; Institute of Health and Biomedical Innovation” This study aimed to identify unknown genetic risk loci associated with androgenetic alopecia by examining SNPs at 12 genomic loci but did not find complete heritable risk factors.
January 2012 in “Faculty of Health; Institute of Health and Biomedical Innovation” This study found six new genetic factors linked to early-onset androgenetic alopecia and its association with increased risk of Parkinson's disease and decreased fertility.
133 citations
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November 2018 in “Aging” This study identified Azithromycin and Roxithromycin as novel senolytic antibiotics that effectively target and reduce senescent human fibroblast cells.
103 citations
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April 2010 in “Journal of Investigative Dermatology” This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.
39 citations
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November 2021 in “Clinical Endocrinology” This review discusses a new multidisciplinary guideline for treating male hypogonadism and emphasizes a comprehensive approach but reports no new experimental results.