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    Did you mean 14,15-Epoxyeicosatrienoic acid?
    Glossary 14,15-Epoxyeicosatrienoic acid

    molecule derived from arachidonic acid involved in vascular function

    14,15-Epoxyeicosatrienoic acid (14,15-EET) is a type of molecule derived from arachidonic acid, which is a fatty acid found in the body's cell membranes. It plays a role in various physiological processes, including the regulation of blood pressure, inflammation, and vascular function. 14,15-EET is produced by the action of enzymes called cytochrome P450 epoxygenases and has been studied for its potential protective effects on the cardiovascular system.

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    Research 25

    1. A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid 1998 · 58 citations
    2. Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors 2018 · 16 citations
    3. Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures PLoS ONE · 2013 · 60 citations
    4. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004 · 10 citations
    5. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004
    6. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    7. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Nutrients · 2018 · 19 citations
    8. Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin Cellular & Molecular Biology Letters · 2025
    9. Review of factors affecting the growth and survival of follicular grafts. PubMed · 2010 · 17 citations
    10. Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias Experimental Dermatology · 2018 · 22 citations
    11. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth Pflügers Archiv - European Journal of Physiology · 2022
    12. TRP Channels in Skin Biology and Pathophysiology Pharmaceuticals · 2016 · 124 citations
    13. Niche-dependent immunometabolic regulation of tissue repair and regeneration Immunity & Inflammation · 2026
    14. Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice Parasites & Vectors · 2024 · 2 citations
    15. Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models Archives of Toxicology · 2018 · 38 citations
    16. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling PLoS Biology · 2020 · 32 citations
    17. Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review International Journal of Molecular Sciences · 2022 · 10 citations
    18. The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe? Biomolecules · 2025 · 4 citations
    19. Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection Journal of Nanobiotechnology · 2025
    20. Recent Advances in the Role of Fibroblast Growth Factors in Hair Follicle Growth Biomolecules · 2025
    21. TRPV Channels in Osteoarthritis: A Comprehensive Review Biomolecules · 2024 · 14 citations
    22. The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair International journal of molecular sciences · 2024 · 1 citations
    23. Visualizing Integrative Functioning in the Human Brainstem and Spinal Cord With Spinal Functional Magnetic Resonance Imaging Neurosurgery · 2013
    24. Effective holistic characterization of small molecule effects using heterogeneous biological networks Frontiers in Pharmacology · 2023 · 11 citations
    25. Detection of urine metabolites in polycystic ovary syndrome by UPLC triple-TOF-MS Clinica Chimica Acta · 2015 · 23 citations