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Did you mean 14,15-Epoxyeicosatrienoic acid?

Glossary14,15-Epoxyeicosatrienoic acid

molecule derived from arachidonic acid involved in vascular function

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a type of molecule derived from arachidonic acid, which is a fatty acid found in the body's cell membranes. It plays a role in various physiological processes, including the regulation of blood pressure, inflammation, and vascular function. 14,15-EET is produced by the action of enzymes called cytochrome P450 epoxygenases and has been studied for its potential protective effects on the cardiovascular system.

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Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

60 citations , December 2013 in “PLoS ONE”

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

58 citations , April 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and Delta-Subunit-Containing Gamma-Aminobutyric Acid A Receptors

16 citations , November 2018 in “The journal of pain/Journal of pain”

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

research Fatty Acids and Related Lipid Mediators in the Regulation of Cutaneous Inflammation

28 citations , January 2018 in “Biochemical Society Transactions”

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

research Role of the Soluble Epoxide Hydrolase in Hair Follicle Stem Cell Homeostasis and Hair Growth

June 2022 in “Pflügers Archiv - European Journal of Physiology”

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

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