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    Glossary Triazole Antifungal

    inhibit fungal cell membrane synthesis by targeting specific enzymes

    Triazole antifungals are a class of medications used to treat fungal infections. They work by inhibiting an enzyme called lanosterol 14α-demethylase, which is crucial for the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption weakens the fungal cell membrane, leading to the death of the fungus. Common examples include fluconazole and itraconazole.

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    Research 10 of 146

    1. Minimal systemic exposure of a new topical triazole antifungal, efinaconazole 10% solution, in patients with severe onychomycosis following 28-day treatment Journal of The American Academy of Dermatology · 2013
    2. Non-Albicans Yeast Scalp Infection in a 6-Year-Old Boy: A Case Report of Candida Parapsilosis and Antifungal Susceptibility Testing Zenodo (CERN European Organization for Nuclear Research) · 2023
    3. Itraconazole in the treatment of acute and recurrent vulvovaginal candidosis: comparison of a 1‐day and a 3‐day regimen Mycoses · 2005 · 12 citations
    4. Refractory Dermatophytosis in a Spitz Dog Successfully Managed with Posaconazole in India: A Case Report Preprints.org · 2026
    5. Treatment of invasive aspergillosis with itraconazole The American Journal of Medicine · 1989 · 350 citations
    6. Formulation And Evaluation Of Emulgel Of An Antifungal Drug For Topical Drug Delivery Journal of Pharmaceutical Negative Results · 2023 · 3 citations
    7. Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort Antimicrobial agents and chemotherapy (Print) · 2018 · 6 citations
    8. The Role of Cytochrome P-450 in Dermatology International Journal of Dermatology · 1989 · 8 citations
    9. Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents Drugs · 2019 · 90 citations
    10. Systemic Antifungals Springer eBooks · 2018
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