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Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

A high-fat diet may weaken tongue structure by reducing certain protein genes.

The local environment is crucial for cell development in the tongue.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.

Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.

The document is a detailed medical reference on skin and genetic disorders.

Tigers had a skin condition causing hair loss and inflammation, but the cause is unknown and treatment didn't work.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Activin A and follistatin control when hair cells develop in mouse ears.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

New treatments targeting specific genes show promise for treating keratin disorders.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

The EDAR gene mutation leads to thinner and more deformed hair shafts.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

RANK-RANKL signaling is essential for hair growth and skin health.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Psychotropic drugs can cause hair loss or excessive hair growth.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

The gene Prss53 affects hair shape and bone development in rabbits.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.