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Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Aromatherapy with certain essential oils is a safe and effective treatment for hair growth in alopecia areata patients.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

Neurosteroids show promise for treating epilepsy and more research is needed.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Agmatine may help reduce seizures linked to hormone changes in female rats.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Letrozole reduces seizures but not brain damage in mice.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.