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The researchers reported that hair follicle germinative epidermal cells can form complex structures when associating with papilla cells in culture, unlike other types of epidermal cells.

Non-thermal plasma helps hair grow by improving the area around hair follicles.

This review examines the challenges of hair follicle regeneration and outlines strategies for bioengineering human hair follicle models, without presenting new experimental results.

This study identified and characterized progenitor cells from equine feet that may play a role in the pathogenesis and recovery of laminitis, suggesting potential therapeutic targets for treatment.

This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

This article reviews how the microenvironment influences adult stem cell behavior and discusses strategies to enhance stem cell function but reports no new experimental results.

This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.

This review explores the regenerative potential of hair follicles and their role in complete skin regeneration, emphasizing the influence of mechanical factors and niche signaling pathways on hair growth and loss.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.

In this study, researchers used patient-derived organoids to model metastasis in colorectal cancer and discovered that cancer cells temporarily switch to a wound-healing program, orchestrated by reduced EZH2 activity and YAP signaling, before spreading to new organs.

This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.

In this study, mice lacking the Mcpip1 gene in their myeloid cells did not develop SCC-like tumors but instead showed increased melanocyte activity and hair loss, indicating a distinct role for myeloid Mcpip1 in skin cancer development compared to keratinocyte Mcpip1.

IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.

This study observed that in aged mouse skin, there was an increase in IL-17-expressing T helper cells, γδ T cells, and innate lymphoid cells, and blocking IL-17 signaling reduced skin inflammation and delayed age-related changes, suggesting it as a potential target to mitigate skin aging.

This study reported significant upregulation and release of S100A4 in psoriatic skin, which may actively contribute to psoriasis pathogenesis.

In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.

This review summarizes existing evidence on how YAP and TAZ proteins are activated in epidermal keratinocytes and their role in coordinating with other signaling molecules to control transcription and influence epidermal cell fate, highlighting their importance beyond the Hippo pathway.

This study reveals that basement membrane composition and structure in mouse hair follicles are specialized for distinct inter-tissue interactions, with laminin α5 being essential for maintaining these interfaces.

This review discusses the potential of endogenic and exogenous exosomes in dermatology and cutaneous aesthetics, highlighting their capacity to repair and rejuvenate skin tissue, but reports no new experimental results.

This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.

This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.

This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This study suggests that Lrig1-positive cells form a previously unknown reservoir of interfollicular epidermal stem cells in adult mouse skin, influencing epidermal proliferation and hair follicle development.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This study found that Notch signalling promotes differentiation of epidermal cells and acts as a tumour suppressor in the skin by interacting with various pathways and mechanisms.