21 citations
,
August 2016 in “Translational Andrology and Urology” This review discusses the pathophysiology of delayed ejaculation, highlighting the role of various biogenic and psychogenic factors, but reports no new clinical findings.
20 citations
,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.
16 citations
,
June 2025 in “Journal of Composites Science” This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.
15 citations
,
November 2002 in “Cardiology in Review” This review discusses various adverse skin reactions linked to cardiovascular medications and reports no new clinical results, highlighting the need for vigilance when prescribing these drugs.
15 citations
,
January 2002 in “Gynecological endocrinology” This review discusses the extragenital effects of ovarian steroids, particularly focusing on aesthetic endocrinology, which suggests estrogens may slow skin aging post-menopause, though hair loss treatment efficacy is mainly confirmed for minoxidil.
14 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This review discusses the fertility and pregnancy challenges faced by women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency and reports no new research findings.
14 citations
,
March 2010 in “Gynecological endocrinology” This article provides an overview of treatment options for hirsutism, summarizing both pharmacologic and non-pharmacologic approaches, but reports no new clinical results.
12 citations
,
October 1995 in “The Journal of Clinical Endocrinology & Metabolism” Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
11 citations
,
March 2019 in “EMBO molecular medicine” This paper reviews the role of endoplasmic reticulum stress and the unfolded protein response in Hutchinson-Gilford progeria syndrome-related atherosclerosis, especially in vascular smooth muscle cells, but reports no clinical findings; intervention in these pathways is suggested as a potential therapeutic strategy.
11 citations
,
March 2016 in “Translational Andrology and Urology” This review highlights the potential therapeutic applications of nandrolone, an anabolic steroid, for male health, but notes that more human studies are needed due to limited existing literature.
11 citations
,
January 2016 in “The Journal of Sexual Medicine” This study found that young women with nonclassic congenital adrenal hyperplasia had impaired sexual function and mild depressive symptoms compared to healthy women.
10 citations
,
April 2020 in “Clinics in Dermatology” This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.
9 citations
,
January 1997 in “Gynecological Endocrinology” This review discusses the regulation of hair growth, causes of excessive androgen secretion, and current safe solutions for hyperandrogenism manifestations in women but reports no new clinical results.
9 citations
,
February 1996 in “Lancet” In this study, reversible ageusia in a patient was strongly suggested to be caused by losartan, with potential implications for angiotensin receptor involvement in taste disturbance.
8 citations
,
May 2017 in “Current traditional medicine” This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.
7 citations
,
September 2024 in “International Journal of Molecular Sciences” This study found that 11-oxygenated androgens were higher in women with PCOS compared to those with idiopathic hirsutism, with no difference from controls, and higher Bisphenol A levels in obese women with PCOS may worsen metabolic issues.
7 citations
,
January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
6 citations
,
July 1990 in “The Journal of Pediatrics” A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
5 citations
,
March 2020 in “Current Opinion in Endocrine and Metabolic Research” This review discusses the contribution of non-androgen causes to acne and female pattern hair loss in PCOS and emphasizes the need for targeted treatment approaches without relying on hyperandrogenism as a diagnostic marker.
5 citations
,
April 2013 in “Current Problems in Pediatric and Adolescent Health Care” This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.
4 citations
,
January 2023 in “Pharmacology” This study found that euthyroid women with Hashimoto’s thyroiditis experienced less benefit from atorvastatin treatment in terms of cardiometabolic marker improvements compared to women with hypercholesterolemia but without thyroid issues, indicating a differential response in these populations.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
3 citations
,
May 2023 in “Biomedicines” This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.
3 citations
,
January 2010 in “Actas Dermo-Sifiliográficas” This paper reviews the growing use of psychotropic drugs in dermatology due to the link between mental states and skin conditions but does not present new clinical findings.
3 citations
,
January 2007 in “Elsevier eBooks” The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
2 citations
,
May 2025 in “Frontiers in Pharmacology” In this study, analysis of FDA data revealed a substantial risk of dermatologic adverse events with aromatase inhibitors, especially anastrozole and exemestane, highlighting the importance of dermatologic monitoring during such therapies.
2 citations
,
December 2024 in “Children” The authors of this review explore the link between thyroid disorders and skin conditions in children, highlighting how conditions like chronic urticaria, vitiligo, and alopecia may signal underlying thyroid issues and emphasizing the importance of early detection for timely diagnosis and personalized treatment.
2 citations
,
June 2023 in “Journal of cell science” In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.
2 citations
,
July 2022 in “Asian Journal of Microbiology, Biotechnology & Environmental Sciences” This review highlights zinc's crucial role in both plant growth and human health, while noting the widespread problem of zinc deficiency in various soils, but reports no new findings.
2 citations
,
January 2019 in “Indian Dermatology Online Journal” This paper summarizes the foundation and proceedings of the first International Congress of SAARCUM, which addressed the growing issue of antifungal therapy failures in South Asia but reports no new research findings.