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The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Hair loss and excessive growth treated with various options, including new laser technology.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Both drugs lower DHT levels, with GI198745 being more effective.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Drinking kava tea can cause a skin reaction with red, swollen bumps, which may improve with steroids.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.