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Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.

This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.

This article summarizes findings on the role of androgens and estrogens in male reproductive tissues across species, highlighting the roles of hormone metabolism, receptor distribution, and stress-induced changes.

This case study of a subfertile couple highlighted the importance of considering haemochromatosis, particularly involving the C282Y mutation of the HFE gene, in patients with endocrine disorders linked to hypogonadism.

This preliminary study of Alopecia Areata identified limited expression of certain metabolic transporters and enzymes in hair follicle immune cells, providing early insight into their unique energy needs.

This case report describes the occurrence of juvenile diabetes mellitus with concurrent exocrine pancreatic insufficiency in a Thai Bangkaew dog, highlighting its successful management with insulin, pancreatic enzymes, and methylcobalamin.

This review introduces in vitro evaluation methods for whitening, anti-wrinkle, and hair growth cosmetic ingredients but reports no new experimental results, highlighting the need for better human-correlated methods and reliable biomarkers.

This study identified the presence of the enzyme 1 alpha-hydroxylase in various extrarenal tissues, suggesting its potential role in modulating vitamin D function in peripheral tissues.

In this study, sirolimus treatment reduced the size of venous malformations and improved anemia, transfusion dependence, and quality of life in patients with blue rubber bleb nevus syndrome, though mild adverse effects were reported.

This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.

In this study, a patient with cystic fibrosis developed iatrogenic Cushing's syndrome due to impaired clearance of budesonide from concurrent itraconazole use, highlighting the need for regular monitoring in such combination therapies.

This case study observed that long-term itraconazole and budesonide use in a cystic fibrosis patient led to iatrogenic Cushing's syndrome due to inhibited metabolic clearance of budesonide, suggesting a need for regular adrenal insufficiency monitoring in such treatments.

This study found that mice lacking the 1αOHase enzyme, which is responsible for producing a key vitamin D metabolite, showed impaired epidermal differentiation and delayed recovery of skin barrier function after disruption.

This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

In this study, albendazole treatment in patients with hydatid disease was associated with decreased microsomal enzyme function and induced its own metabolism, but also showed potential hepatotoxicity and severe side effects, necessitating careful monitoring.

This study observed that knocking out the 1α-hydroxylase gene in mice resulted in rickets and growth retardation, demonstrating the enzyme's crucial role in vitamin D function in animals.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This study found that individuals with homozygous loss-of-function mutations in PLAAT3 experience a novel type of partial lipodystrophy linked to defects in white adipose tissue differentiation and function.

This study found that the enzyme encoded by Dgat1 acts as a retinol acyltransferase in murine epidermis, protecting against retinoid toxicity and alopecia by preventing retinol accumulation.

This review discusses the effects of neuroactive testosterone metabolites on CNS functions and suggests their potential as therapeutic options for neurological disorders, but reports no new clinical results.

Congenital Adrenal Hyperplasia is mainly caused by enzyme deficiencies, leading to varying symptoms like hormone imbalances and physical changes.

This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.

This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.

This review explores the potential of nanozymes as artificial enzymes with diverse applications but highlights the need for more research into their mechanisms, safety, and scalability before they can be effectively translated into clinical use.

In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.

This review highlights zinc's role in health and disease, noting its involvement in immune function and its therapeutic potential for conditions like alopecia areata and psoriasis, but it reports no new clinical results.

This study presents the crystal structure of human SRD5A2 with finasteride and reveals insights into its enzyme catalysis and inhibition mechanisms, which may inform drug development.

This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.

This review discusses the role of RDH12 in vision, its structural and functional aspects, and related disease mechanisms, but reports no new clinical results; it aims to support therapy development for inherited retinal dystrophies.