research Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
Blocking Prostaglandin D₂ may help treat hair loss.
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research Carica Papaya Flower Extracts Possess Antioxidant and 5α-Reductase Inhibitory Activities
Papaya flower extract may help with hair growth by blocking a hair loss enzyme and acting as an antioxidant.
research The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice
Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation
Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
research The Hair Growth Promoting Effect of Sophora Flavescens Extract and Its Molecular Regulation
Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
research Purification and Characterization of Rat Liver Minoxidil Sulphotransferase
Enzyme purified and characterized for minoxidil sulphation in rat liver.
research Loss of UBE2N in Keratinocytes Leads to Skin Inflammation and Immune Infiltration Through IRAK1/4-Mediated Processes
Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity
Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
research Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice
Costunolide helps human hair cells grow and can stimulate hair growth in mice.
research Defining Metabolic Flexibility in Hair Follicle Stem Cell Induced Squamous Cell Carcinoma
Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
research Hair Loss and Hirsutism in the Elderly
Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.
research Minoxidil Use in Androgenic Alopecia
Minoxidil helps stimulate hair growth and enlarge small follicles in common hair loss, but doesn't stop it, and its effects can be boosted when combined with finasteride.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis
Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.
research Angiogenin Is Expressed in Human Dermal Papilla Cells and Stimulates Hair Growth
Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Topical Metformin as a Novel Therapy for Alopecia Areata Due to Its Immunologic Effects
Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Preparation of a Highly Specific Single Chain Variable Fragment Antibody Targeting Miroestrol and Its Application in Quality Control of Pueraria Candollei by Enzyme-Linked Immunosorbent Assay
The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Endocrinological Evaluation and Hormonal Therapy for Women with Difficult Acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
research Hair Follicles, Their Disorders, and Their Opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Inhibition of the Pro-Oxidant Effects of Benoxaprofen on Polymorphonuclear Leucocytes by Retinol Acetate In Vitro
Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.