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Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Gene mutations can cause problems in male genital development.

iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.

Using enzymes to link proteins makes hair repair treatments more effective and long-lasting.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Skin grafting is a key procedure for repairing skin defects, with the success depending on the right graft choice, donor site management, and aftercare.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Hair color is influenced by genetics and can indicate certain health conditions.

New genes and pathways are important for testosterone production and male sexual development.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

Oregano extract helps fix testis and sperm damage caused by finasteride.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

The conclusion suggests a new way to classify bradykinin-mediated angio-oedema based on different causes and its possible link with urticaria, which could improve diagnosis and treatment.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.