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A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Cannabinoids may help treat various skin conditions.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Mice with autoimmune hair loss showed signs of heart problems.

Wound healing is complex and requires more research to enhance treatment methods.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Dermal factors are crucial in regulating melanin production in skin.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.

Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.