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    GlossaryEndothelin-1

    potent vasoconstrictor peptide regulating blood vessel constriction

    Endothelin-1 (ET-1) is a potent vasoconstrictor peptide produced by endothelial cells, which line the blood vessels. It plays a crucial role in regulating blood pressure and vascular tone. Elevated levels of ET-1 are associated with various cardiovascular diseases, including hypertension and heart failure.

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