155 citations
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March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
56 citations
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July 2008 in “European journal of endocrinology” This study found that a 6-month treatment with either metformin or rosiglitazone significantly improved endothelial function in young women with PCOS without any one drug being superior.
44 citations
,
May 2008 in “Fertility and Sterility” In this study, young, nonobese PCOS patients showed significant insulin resistance, but no significant difference in endothelial function compared to healthy controls, suggesting other factors may influence endothelial health.
27 citations
,
August 2006 in “Laboratory Investigation” In this study, the combination of SCF and ET-1 was found to significantly enhance skin pigmentation and melanin content in human skin xenografts on SCID mice compared to either treatment alone.
11 citations
,
August 2006 in “Cell Biology International” This study found that endothelin-1 increases adhesion and chemotaxis of amelanotic melanocytes on fibronectin, laminin, and collagen IV, potentially through changes in the actin cytoskeleton.