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COVID-19 may lead to severe skin necrosis without clear underlying causes, as seen in a diabetic patient who required leg amputation.

Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Nerves are crucial for the regeneration of various body parts in many animals.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Hair follicle regeneration needs special conditions and young cells.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Fat cells are important for tissue repair and stem cell support in various body parts.

Cell aging can be both good and bad for tissue repair.

Soy isoflavones can protect lung tissue from radiation damage.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Using micro skin tissue columns improves skin wound healing and reduces scarring.

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.