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Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Minoxidil may help prevent capsular opacification after cataract surgery.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Apoptosis is essential for human skin development and forming a functional epidermis.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Telocytes might help with skin repair and regeneration.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Wool follicles are complex, involving interactions between different cell types and structures.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

TPA is about 50 times more effective at promoting tumors than MZ.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.