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Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.

Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

Squalene may be a marker for certain types of alopecia.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

Various treatments effectively manage androgenetic alopecia.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Some overweight or obese men with long-term frontal fibrosing alopecia may have abnormal sex hormone levels.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

A woman with asthma improved from a severe fungal infection after treatment change, and most HIV-positive women in a UK study had low immune cell counts but were responding well to treatment.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Finasteride improves hair growth in men with androgenetic alopecia.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.

Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Premature graying of hair is common and stressful, but not well understood or treated.

Oral tranexamic acid is a safe and effective treatment for melasma.

A woman lost over 80% of her hair due to a condition called telogen effluvium after having COVID-19.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Telogen Effluvium is a common, usually reversible hair loss condition, often improved by removing the trigger and possibly treated with various products, though their effectiveness is uncertain.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

PGD2 stops hair growth and is higher in bald men with AGA.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.