1 citations
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February 2025 in “Journal of Endocrinological Investigation” This review discusses the prevalence and clinical impact of menstrual abnormalities, acne, and hirsutism in young women with Cushing's syndrome and reports no new clinical results.
April 2026 in “Almanac of Clinical Medicine” In this study, pemphigus vulgaris patients treated with high-dose prednisolone developed symptoms similar to those seen in corticosteroma, such as weight gain and muscle weakness, with increased risks of arterial hypertension and glucose metabolism disorders after 6 months of therapy.
March 2026 in “Lithuanian University of Health Sciences” In this case report, a rare instance of ACTH-independent hypercortisolism in a patient with long-standing Addison's disease led to the discovery of an adrenal cortical adenoma, successfully treated with adrenalectomy, underscoring the importance of considering functional adrenal tumors in such atypical biochemical scenarios.
November 2022 in “Journal of the Endocrine Society” This case report describes a patient with ectopic Cushing's syndrome who experienced fatal complications from COVID-19, highlighting the challenges in managing such patients due to immune response alterations from endogenous hypercortisolemia.
January 2020 in “Frontiers in Medical Case Reports” This case study reported that reducing glucocorticoids resolved calcinosis cutis in a dog with hypoadrenocorticism, while demodicosis was treated with a fluralaner chewable tablet.
9 citations
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April 2020 in “Endocrinology, diabetes & metabolism case reports” This case study highlights the significance of early diagnosis and treatment of Cushing's syndrome during pregnancy, as it is associated with severe maternal and fetal complications, including stillbirth.
3 citations
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December 2017 in “Journal of Psychiatric Research” This study found that hair cortisol did not indicate expected hypercortisolism in acutely underweight anorexia nervosa patients and did not change significantly during short-term weight restoration.
February 2024 in “Animals” In this study, dogs with adrenal-dependent hypercortisolism showed a decrease in the prevalence of systemic hypertension from 79% to 25% after a year of trilostane treatment or adrenalectomy, with blood pressure normalization observed by three months post-surgery in hypertensive dogs.
18 citations
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April 2011 in “Neuropharmacology” This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.
April 2020 in “Journal of the Endocrine Society” This study suggests that hair cortisol measurement could serve as an alternative diagnostic method for Cushing’s disease, showing acceptable concordance with urinary free cortisol despite differing evaluated periods.
175 citations
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January 2020 in “European Journal of Endocrinology” These guidelines recommend testing thyroid function in patients with obesity due to common hypothyroidism, and highlight that weight loss is crucial for addressing hormonal imbalances, with only modest weight loss benefits from treating endocrine disorders.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.
5 citations
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February 2023 in “European journal of endocrinology” This study found that older patients with Cushing's syndrome had fewer typical symptoms of hypercortisolism, more comorbidities, and were more often treated conservatively compared to younger patients.
November 2022 in “Journal of the Endocrine Society” This case report suggests that genetic evaluation for glucocorticoid resistance, such as the NR3C1 gene variant, is crucial for proper diagnosis and management of patients showing atypical signs of hypercortisolism.
4 citations
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March 2013 in “Neuropsychiatric Disease and Treatment” This case report describes a rare instance of a patient with anorexia nervosa who was subsequently diagnosed with Cushing's syndrome, highlighting diagnostic challenges due to overlapping symptoms.
30 citations
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November 2021 in “Obesity Reviews” This meta-analysis found a consistent positive association between glucocorticoids in hair and obesity measures, with the relationship between hair cortisone and waist circumference being particularly clinically relevant.
July 2023 in “JCEM Case Reports” This case study describes a 36-year-old woman with a history of recurrent limb weakness linked to hypokalemia and later diagnosed with Cushing syndrome indicated by elevated cortisol levels and a pituitary mass, which was treated with surgery and radiosurgery.
374 citations
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May 2016 in “The Lancet. Diabetes & endocrinology” This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
42 citations
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November 2019 in “Frontiers in Endocrinology” This article provides an overview of diagnosing Cushing's syndrome, emphasizing the importance of assessing clinical signs and the appropriate use of first-line biochemical screening.
38 citations
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January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
51 citations
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November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
January 2018 in “Karger Kompass” This study reports a case of a woman with Cushing's disease whose initial complaint was hair loss, a rare presenting symptom, despite multiple dermatological signs like easy bruising and violaceous striae being more indicative of the condition.
June 2025 in “Journal of Endocrinological Investigation” This review identifies and discusses various endocrine-related causes of hypertension in children and adolescents, emphasizing the role of genetic predispositions and highlighting the need for systematic diagnostic guidelines and genetic sequencing referrals to improve diagnosis and treatment strategies.
91 citations
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May 2005 in “The Journal of Clinical Endocrinology & Metabolism” In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.
86 citations
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October 2017 in “Translational pediatrics” This review discusses how ophthalmic findings can reveal key endocrine disorders and reports no new clinical results, emphasizing the eye's role in diagnosing and managing systemic diseases like diabetes and Graves' ophthalmopathy.
35 citations
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March 2012 in “Experimental and Clinical Endocrinology & Diabetes” This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.
23 citations
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February 1979 in “Veterinary Clinics of North America: Small Animal Practice” This review discusses the physicochemical properties, binding mechanisms, and factors affecting corticosteroid-binding globulin (CBG) functions, but reports no new clinical results.
18 citations
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January 2004 in “Dermatologic Clinics” This article discusses nutritional contributions to hair health and highlights the need for identifying risk factors for deficiencies but reports no new clinical findings.
12 citations
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December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
6 citations
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February 2017 in “Case Reports in Dermatology” This case report highlights that hair loss, though common in the general population, may be a rare presenting symptom of Cushing's disease, as observed in a woman with multiple dermatological signs of the condition.