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Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

Prolactin slows down hair growth in mice.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Androgens prevent hair growth by changing Wnt signals in cells.

Spironolactone plus finasteride reduces hirsutism more effectively.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.

Melatonin protects skin against UV damage by regulating various cellular processes.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.