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Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Fish oil improves skin health in people with diabetes and high cholesterol.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Hormonal therapies are safe and effective for treating adult women's acne.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.