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This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.

This review highlights the promising potential of 3D printing for creating microneedles with precise customization and improved performance compared to traditional micromolding, emphasizing applications in personalized medical devices and advancements in biomedical fields.

This article discusses the potential of novel microneedle transdermal systems for enhanced drug and vaccine delivery through the skin, but reports no clinical results and emphasizes ongoing trials.

This systematic review examines the landscape of cosmetic microneedling using SWOT analysis, identifying strengths like precise delivery and self-administration, while noting challenges such as potential skin damage and regulatory issues, with opportunities in AI-enhanced targeted treatments noted by these researchers.

This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.

This article reviews microneedle technology as a transdermal drug delivery platform without presenting new clinical results, emphasizing its engineered microstructure arrays for enhanced penetration.

This study developed a personalized microneedle that delivers finasteride directly to the skin, facilitating a sustained release and potentially reducing side effects associated with oral administration.

This review discusses the challenges of traditional phytochemical delivery methods and highlights the potential of microneedles to improve intra/transdermal delivery, reporting no new clinical results.

This study found that finite element analysis-guided design improved bubble microneedles' controlled tip separation and insertion strength, supporting effective transdermal and sublingual drug delivery.

This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.

This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.

This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.

This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.

This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.

This review highlights that microneedling is an effective and flexible technique for enhancing transdermal drug delivery, with numerous applications in both cosmetic and therapeutic dermatological treatments. The researchers note that further advancements are likely to increase its efficacy and safety.

This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.

This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.

This review discusses the applications and potential of microneedles loaded with extracellular vesicles for tissue regenerative repair and disease diagnosis, but does not report new experimental findings.

This review discusses the potential of microneedles in cancer diagnosis and treatment, highlighting advances and ongoing clinical trials, but reports no new results; it emphasizes the minimally invasive nature of this technology.

This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.

This study explores the use of bioinspired 3D printed hollow microneedles, which may offer improved delivery of anti-wrinkle formulations, and reviews the current landscape and challenges of existing wrinkle treatments and microneedle technology.

This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.

This review discusses the cosmetic applications and healing phases of microneedling and reports no new clinical findings; the authors highlight its use for skin and hair treatments without epidermal damage.

This review discusses the safety and potential adverse events of microneedling as both a medical and consumer product, noting the need for further understanding; no new clinical results are presented.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.