8 citations
,
March 2018 in “Expert Review of Respiratory Medicine” This article reviews the potential of inhalation therapy to restore pulmonary elastin fibers in COPD patients and highlights the need for studies to test its feasibility; it reports no new research findings.
20 citations
,
January 2005 in “Australasian Journal of Dermatology” This article describes a case of late-onset focal dermal elastosis in a 73-year-old woman, characterized by flat pale yellow lesions and increased normal elastic fibers, distinct from pseudoxanthoma elasticum.
February 2026 in “Cosmetics” This review examines the clinicopathologic features of perifollicular elastolysis and indicates that, while its presentation is consistent, there is a lack of high-certainty evidence for effective treatments.
November 2024 in “Journal of Investigative Dermatology” In this study, UVB irradiation increased mast cell degranulation only when skin was innervated, suggesting that the interaction between mast cells and nerve fibres may exacerbate solar elastosis by promoting dysfunctional dermal elastic fiber accumulation, but further research is needed for confirmation.
September 2022 in “Anais Brasileiros de Dermatologia” This case study reports a female adult patient with annular elastolytic giant cell granuloma on the scalp, observed through dermoscopy showing multiple yellowish/orange follicular dots against an erythemato-whitish background.
February 2023 in “Journal of Cutaneous Pathology” This case report describes an adult female with concurrent mycosis fungoides and papillary dermal elastolysis, highlighting the importance of considering rare presentations in differential diagnoses.
10 citations
,
October 2018 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the skin and systemic conditions associated with Down syndrome and reports no new clinical results, emphasizing the need for awareness of these manifestations in diagnosis.
This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.
October 2022 in “Skin appendage disorders” This study found that isolated scalp microneedling did not improve scalp coverage or hair density in male pattern hair loss patients, with no adverse events reported.
39 citations
,
March 1997 in “The Lancet” Acquired perforating dermatosis often affects skin in people with kidney issues and diabetes.
June 2024 in “British Journal of Dermatology” In this prospective observational study of 96 dermatomyositis patients, 47 showed scalp involvement, with significant symptoms like scalp inflammation, itching, and hair loss linked to myositis-specific antibodies. The study highlighted unique dermatopathological features in the scalp and emphasized the considerable morbidity caused by scalp dermatomyositis.
September 2022 in “Scientific Reports” This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.
This study found that scalp melanoma in areas with androgenetic alopecia presents with more frequent detrimental mutations and may have a poorer prognosis due to late diagnosis linked to hair concealment.
27 citations
,
July 2020 in “Stem Cells International” This study observed that while PRP therapy increased inflammation and fibrosis in photoaged skin, ADSCs therapy showed promising antiaging effects by promoting elastin and fibrillin formation and remodeling the dermis.
27 citations
,
January 2002 in “Exogenous Dermatology” In this study, researchers reported that chronic UV exposure may contribute to androgenic alopecia progression by influencing hair cycle changes and exacerbating solar elastosis in the scalp.
9 citations
,
September 2009 in “Journal of Cutaneous Medicine and Surgery” This study reports cases of androgenetic alopecia patients with depigmented macules on sun-exposed scalp areas, suggesting potential ultraviolet-induced scalp leukoderma not covered in existing dermatology texts.
8 citations
,
January 2013 in “BioMed Research International” This study observed that both Factor XIIIa+ dermal dendrocytes and microvasculature size decreased with scalp aging and that alopecia changes resembled stress-induced premature senescence.
3 citations
,
May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
2 citations
,
March 2019 in “Experimental Techniques in Urology & Nephrology” This article reviews the dermatologic conditions associated with hemodialysis, such as pruritus, xerosis cutis, and skin infections, and does not present new findings.
July 2020 in “Experimental Dermatology” This discussion of age-related changes in female scalp hair follicles reports no new results, highlighting the structural transformations that may contribute to thinning hair in women as they age.
This study suggests that pseudopelade may be an autonomous disease based on its distinctive clinical and histopathological features not present in other scarring alopecias.
38 citations
,
December 2012 in “Journal of Cutaneous Pathology” This review discusses the significance of elastic tissue staining in dermatopathology, particularly for diagnosing primary elastic tissue disorders and other skin conditions, but reports no new clinical results.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
6 citations
,
January 1967 in “Journal of Small Animal Practice” This study observed that aged dogs exhibit atrophy of the epidermis, appendages, and dermis, along with variable skin changes and increased dermal pigmentation, but lack senile elastosis seen in humans.
15 citations
,
September 2014 in “Journal of The American Academy of Dermatology” This study found that seven cases of cicatricial alopecia initially diagnosed as discoid lupus erythematosus were more consistent with lichen planopilaris based on histopathology.
14 citations
,
October 2021 in “Dermatology and Therapy” This study found that photoexposure significantly increased the gene expression of altered elastin, MMP12, and LOX, as well as the protein expression of tropoelastin and fibrillin-1, in skin models.
33 citations
,
November 1994 in “Archives of Biochemistry and Biophysics”
30 citations
,
November 2013 in “Journal of The American Academy of Dermatology” This study reported that patterns of fibrosis identified through elastin staining may help distinguish specific forms of primary cicatricial alopecia in biopsy specimens, with certain patterns suggesting particular diagnoses.
62 citations
,
January 2003 in “Dermatology” This review suggests that androgenetic alopecia may be exacerbated by exposure to ultraviolet radiation and proposes considering it as a photoaggravated condition requiring photoprotection.
41 citations
,
August 1988 in “Journal of The American Academy of Dermatology” In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.