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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Blocking Prostaglandin D₂ may help treat hair loss.

Hair loss linked to kidney stones in people under 60.

Patients with chronic kidney disease on hemodialysis often have skin problems.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The patient's high testosterone was reduced by a medication that suppresses gonadotropin.

Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Excess androgens may cause PCOS, not just be a symptom.

Effective PCOS treatments require targeting specific signaling pathways.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Targeted immunotherapy could be a promising new treatment for hair regrowth.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.

The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

NOC-4 extract promotes black hair and hair growth effectively.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

A specific genetic deletion in goats affects cashmere yield and thickness.