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Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

SHBG may be a useful early indicator and treatment target for PCOS.

The document concludes that electrolysis and thermolysis can permanently remove hair but calls for better regulation to ensure safety, and notes a possibility of hair regrowth and rare complications.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Improving the environment and cell interactions is key for creating human hair in the lab.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Minoxidil helps hair regrowth in alopecia areata safely.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

K16 can partially replace K14 but causes hair loss and skin issues.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.