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research 838 Histologic and immunohistochemical evaluation of Lichen Planopilaris and correlation with clinical disease severity
In this pilot study, researchers observed a correlation between clinical severity and histologic severity of lichen planopilaris, suggesting that an immunohistochemical scoring system could aid in grading disease activity.
research Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis
Ceramide Synthase 4 is crucial for healthy skin barrier function.
research Maladaptive Daydreaming in Psoriasis Patients
This study investigated whether individuals with psoriasis have higher MDS-16 scores and potentially more maladaptive daydreaming compared to healthy individuals.
research A Case Report of Cronkhite-Canada Syndrome Complicated by Membranous Nephropathy
This case report detailed a 71-year-old male with Cronkhite-Canada syndrome and associated membranous nephropathy, who showed a significant improvement in skin and gastrointestinal symptoms, and remission of nephropathy, after treatment with rituximab, cyclosporine, and azathioprine.
research LB1020 Scurvy: A forgotten illness?
This case report reveals a diagnosis of scurvy in a 19-year-old woman, emphasizing the importance of considering vitamin C deficiency in patients with dietary restrictions presenting with specific skin and gum symptoms.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets.
This review discusses the role of epidermal differentiation complex genes and epigenetic mechanisms in skin development and certain diseases, emphasizing their potential for improving drug development and delivery systems but provides no new experimental results.
research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases
This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.
research P050 Rapidly worsening subcutaneous oedema in a young boy: a case of juvenile dermatomyositis
This case study describes a 4-year-old boy with juvenile dermatomyositis whose severe subcutaneous edema resisted conventional treatment, necessitating aggressive immunosuppression for disease control.
research 0475 High-dose UVA-1 therapy improves patient-reported outcomes and clinical scores in patients with sclerosing skin disease
This study found that high-dose UVA-1 therapy appeared to improve both patient-reported outcomes and objective clinical measures in patients with morphea and systemic sclerosis, supporting its potential efficacy for treating scleroderma.
research Progress in studies of epidermal stem cells and their application in skin tissue engineering
This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.
research Netherton Syndrome: A Case-Based Review of Diagnosis, Management, and Emerging Treatments.
This case study reports that early genetic testing and targeted therapies, such as secukinumab, can significantly improve skin barrier function in patients with Netherton syndrome, despite persistent symptoms.
research Oral Presentations
The document concludes that an experimental drug may help wound healing in Epidermolysis Bullosa, links Hydroa vacciniforme to EBV, discusses diagnosing hair loss disorders, finds many children with eczema have allergies, reviews the safety of a skin medication in children, notes side effects of a Duchenne's treatment, and identifies a marker for pediatric mastocytosis.
research Erosive Pustular Dermatosis of the Scalp Induced by Imiquimod
An 84-year-old man got a rare scalp condition from using imiquimod cream, which was cured with systemic steroids.
research Primary Cutaneous Rhabdoid Squamous Cell Carcinoma: A Case Report and Review of Molecular Features
This case report describes a rare aggressive variant of squamous cell carcinoma on the scalp of a non-immunosuppressed older male, highlighting its high biological risk for metastasis and poor outcomes.
research The Comparative Safety of Epirubicin and Cyclophosphamide versus Docetaxel and Cyclophosphamide in Lymph Node-Negative, HR-Positive, HER2-Negative Breast Cancer (ELEGANT): A Randomized Trial
In this study, EC chemotherapy was found to be noninferior to TC in causing grade 3 or 4 neutropenia among HR+/HER2-negative breast cancer patients, but EC was associated with more other adverse events.
research Canine Epidermal Neural Crest Stem Cells: Characterization and Potential as Therapy Candidate for a Large Animal Model of Spinal Cord Injury
This study reports that epidermal neural crest stem cells from dogs (cEPI-NCSC) can generate neural crest derivatives and may offer a new cell-based therapy for canine spinal cord injury, with potential as a model for human treatments.
research Cronkhite-Canada syndrome: A rare disease presenting with dermatological and gastrointestinal manifestations
This case report describes a patient with Cronkhite–Canada syndrome, where immunosuppression and nutritional support led to disease remission.
research Cronkhite–Canada syndrome: from clinical features to treatment
This review discusses the characteristics and challenges in treating Cronkhite–Canada syndrome but reports no new clinical findings, emphasizing the need for better understanding and uniform treatment approaches.
research HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
This review discusses drug-induced hypersensitivity syndrome and drug reaction with eosinophilia and systemic symptoms, highlighting clinical features, potential viral reactivations, and treatment, but reports no new clinical findings.
research The Case Files
This article discusses the clinical features, diagnosis, and management of acute radiation syndrome, using a case of a boy exposed to radioactive material in the desert, but reports no new research findings.
research Clinical and Dermoscopic Correlation in Secondary Syphilis: A Report of Three Cases
This study reported that dermoscopy can aid in distinguishing secondary syphilis from other skin conditions by enhancing diagnostic accuracy, though there are no standardized criteria; further research is needed to confirm these findings.
research Outcome domains in lichen sclerosus
This abstract discusses Lichen Sclerosus, a chronic skin condition affecting the genitals, highlighting its symptoms, complications, and impact on quality of life, but reports no new clinical findings.
research Establishment of a murine cGVHD model with scleroderma
This study established a murine chronic graft-versus-host disease model with scleroderma features, showing typical skin changes and cellular infiltrates associated with the condition.
research Comprehensive Evaluation of Neuropsychiatric and Mucocutaneous Manifestations in the Diagnosis of Systemic Lupus Erythematosus: A Complete Clinical Approach to a Case
In this case report, a patient's atypical neuropsychiatric and dermatological symptoms were crucial for diagnosing systemic lupus erythematosus, highlighting the disease's clinical heterogeneity and the importance of early detection to prevent organ damage.
research Unraveling a Rare Case: Diarrhea, Alopecia, and Polyposis
Corticosteroids improved symptoms in a man with Cronkhite-Canada Syndrome.
research Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review
This review categorizes 59 modifications of the Dermatology Life Quality Index across multiple studies, highlighting the need for further validation of these customized health-related quality of life tools in dermatology.
research High-sensitivity C-reactive protein (hs-CRP) levels and its relationship with components of polycystic ovary syndrome in Indian adolescent women with polycystic ovary syndrome (PCOS)
In this study, hs-CRP levels were not significantly associated with PCOS among Indian adolescent women, but showed a positive correlation with body mass index.
research Quality of life in patients with seborrheic dermatitis
This review explores how seborrheic dermatitis impacts patients' quality of life but does not present new research findings; it highlights a need for further studies on influencing factors.
research Novel splicing‐site mutation in DCAF17 gene causing Woodhouse‐Sakati syndrome in a large consanguineous family
This study identified a splicing-site deletion in the DCAF17 gene associated with Woodhouse-Sakati syndrome in a large consanguineous pedigree, leading to typical phenotypic features.