Rapidly Worsening Subcutaneous Edema in a Young Boy: A Case of Juvenile Dermatomyositis

    April 2022 in “ Rheumatology ”
    Shalini Janagan, W. A. E Udeshika, Pasindu M Samarasinghe, Jayatri Jagoda
    Image of study
    TLDR Juvenile dermatomyositis can worsen quickly and needs strong treatment.
    A 4-year-old boy in Sri Lanka presented with generalized rash, facial puffiness, hair loss, and muscle weakness, leading to a diagnosis of juvenile dermatomyositis (JDM). Despite initial treatment with high-dose steroids, his condition worsened with severe subcutaneous edema and muscle power deterioration. Further treatment with IV Methylprednisolone, plasmapheresis, and cyclophosphamide led to improvement, though he remains steroid-dependent and awaits Rituximab treatment. The case highlights the severe, rapidly progressive nature of JDM-associated subcutaneous edema and the need for aggressive immunosuppression for better outcomes.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

    Similar Research

    5 / 1000+ results
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.
      Wound Healing and Hair

      research Wound Healing and Hair

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Certain drugs can cause lupus, stopping these drugs is the main treatment. NB-UVB phototherapy clears psoriasis faster when applied three times a week. Monoclonal antibodies and oral pimecrolimus are effective in treating psoriasis. Smoking and drinking are linked to psoriasis in men. No direct link between low iron and hair loss was found. Vaccines are effective against genital herpes and human papillomavirus type 16.
      Internal Medicine: Retrospective Review of 120 Patients Over a 10-Year Period

      research Internal Medicine: Retrospective Review of 120 Patients Over a 10-Year Period

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Certain drugs can cause skin lupus, but stopping the drug usually helps. Vaccines work against smallpox, genital herpes, and a type of human papillomavirus. More frequent light therapy clears psoriasis faster. Certain treatments work for psoriasis and dermatitis. A specific cream effectively treats a type of skin cancer. Low iron levels aren't directly linked to chronic hair loss.