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270-300 / 1000+ resultsresearch Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty
This study suggests that patients with STSD show a different pattern in androgen activation compared to healthy controls, potentially due to increased 5α-reductase activity and absent prepubertal serum DHEA surge.
research Erosive Pustular Dermatosis: A Manifestation of Immunosenescence A Report of 8 Cases
This series of eight North American patients with erosive pustular dermatosis of the scalp suggests that factors like immunosenescence and ultraviolet damage may contribute to the condition's development.
research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting
This case report discusses the diagnostic challenges and management options for three siblings with 46, XY DSD due to type 2 5-α reductase deficiency, highlighting the genetic basis and impact on their quality of life.
research Clinical Features of Systemic Lupus Erythematosus Patients Complicated With Evans Syndrome
This study reports that systemic lupus erythematosus patients with Evans syndrome often exhibited photosensitivity, hypocomplementemia, and elevated serum IgG, while lupus nephritis was less common, suggesting distinct clinical features.
research Adalimumab improves health-related quality of life (HRQoL) in patients with moderate to severe hidradenitis suppurativa (HS): Results from the first 12 weeks of PIONEER II
Adalimumab significantly improves quality of life for patients with moderate to severe hidradenitis suppurativa.
research 701 Rethinking alopecia scores: Correlating measures of hair loss with established photographic scoring systems
This study suggests that distinct alopecia scoring systems measure percent hair loss as a common underlying feature, with strong correlations observed between different types of hair loss assessments.
research Dermatologic Conditions of the Early Post-Transplant Period in Hematopoietic Stem Cell Transplant Recipients
This review discusses major dermatologic conditions occurring in the early post-hematopoietic stem cell transplant period and reports no new clinical results; it underscores dermatologists' role in recognizing critical complications.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
research Padrão dermatoscópico das alopecias cicatriciais causadas por lúpus eritematoso discoide e líquen plano pilar
This study concluded that dermoscopy enhances the diagnostic capability for cicatricial alopecia beyond clinical inspection and identified novel dermoscopic features such as blue-grey dots.
research Erosive pustular dermatosis of the scalp treated with 0.1% mometasone furoate cream.
In this case report, erosive pustular dermatosis of the scalp in a 49-year-old man showed improvement with daily application of 0.1% mometasone furoate cream.
research Corneal tomography detection of elevated ectasia risk in atopic dermatitis patients with no prior ophthalmologic diagnosis
This study observed that moderate to severe atopic dermatitis patients showed a higher prevalence of keratoconus compared to the general population, with 6.7% having manifest KC and 20% subclinical KC, highlighting the need for increased awareness among dermatologists.
research Dermal safety comparison of 0.05% desonide cream and 1.0% hydrocortisone cream
This study found no significant difference in effectiveness between 0.05% desonide cream and 1.0% hydrocortisone cream for treating seborrheic dermatitis over 8 weeks, with neither causing skin atrophy.
research Scar classification in cutaneous lupus erythematosus: morphological description
This study classified scars in discoid lupus erythematosus patients into six types based on anatomical location and morphology, suggesting early identification might influence more aggressive treatment strategies.
research Comprehensive treatment of Cronkhite-Canada syndrome: A case report and literature review
This review discusses the potential of traditional Chinese medicine to relieve clinical symptoms in cases of CCS and emphasizes the need for further large-scale, long-term studies to verify these effects.
research Cardiac flow parameters with conventional and pulsed tissue Doppler echocardiography imaging in patients with polycystic ovary syndrome
In this study, echocardiographic measures of cardiac function in women with polycystic ovary syndrome were found to be similar to those of healthy women.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.
research Sjogren-Larsson Syndrome
This case report highlights a 21-year-old woman with seizures, mental retardation, spastic diplegia, and ichthyosis consistent with Sjogren-Larsson syndrome, and emphasizes the importance of differential diagnosis when additional symptoms are present.
research MANIFESTATIONS OF EXCESSIVE DAYTIME SLEEPINESS AND GHRELIN LEVEL IN CASE OF GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE
In this study, GERD symptoms were found to be significantly related to acid exposure time and the intensity of excessive daytime sleepiness, which depends on circulating ghrelin levels.
research SnapshotDx Quiz: April 2022
In this study, Wang et al. (2022) found that in patients with cutaneous lupus erythematosus, chronic lesions contained more senescent progenitor cells, marked by p16 and p21, than subacute lesions, suggesting a link between disease chronicity and cellular senescence.
research Riesgo de coagulopatía inducida por sepsis a causa de SARS COV-2 en pacientes en período de gestación
In this study, 86% of pregnant women with SARS-CoV-2 received timely thromboprophylaxis based on their sepsis-induced coagulopathy scores, with most scoring between one and two.
research Epidermal Stem Cells Cultured on Collagen-Modified Chitin Membrane Induce In Situ Tissue Regeneration of Full-Thickness Skin Defects in Mice
This study reports that transplantation of an ESCs-collagen-chitin biomimetic membrane leads to successful in situ skin regeneration, including hair follicle cell proliferation and formation of dermatoglyphs, in nude mice with full-thickness skin defects.
research Arabic version of Skindex‐16: Translation and cultural adaptation, with assessment of reliability and validity
This study translated and culturally adapted the Skindex-16 questionnaire into Arabic, finding it to be a reliable and valid measure of quality-of-life impacts from skin diseases in Saudi patients.
research 652 Short cell cycle duration is a phenotype of human epidermal stem cells
Human epidermal stem cells divide faster than previously thought.
research Circadian rhythm sleep-wake disorders (CRSWDs): Linking circadian misalignment to adverse health outcomes.
This study reports a novel diagnostic method for latent circadian rhythm sleep-wake disorder using circadian gene oscillations from hair follicle cells to improve sleep disorder differentiation and potential therapeutic intervention.
research Do Different Diagnostic Criteria Impact Polycystic Ovary Syndrome Diagnosis for Adolescents?
In this study, the researchers found that the choice of diagnostic criteria significantly affects the rate of PCOS diagnosis in adolescents.
research The Potential Application of Ecklonia cava Extract in Scalp Protection
This study found that Ecklonia cava extract increased skin hydration and decreased redness, suggesting potential benefits for protecting and repairing scalp skin from pollutant-induced damage.
research Smart Bio-Polymeric Matrix for Accelerated Wound Healing and Tissue Regeneration
In this study, researchers modified an acellular scaffold with different concentrations of eggshell membrane protein, finding that a 5% concentration effectively enhanced tissue regeneration in mice with excisional wounds, achieving complete healing within 14 days without causing immunogenicity or inflammation.
research Recombinant Thrombomodulin Used to Successfully Treat Cronkhite-Canada Syndrome with Disseminated Intravascular Coagulation due to Sepsis in a Compromised Patient
In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.
research Facial Psoriasis Log-based Area and Severity Index: A valid and reliable severity measurement method detecting improvement of facial psoriasis in clinical practice settings
The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).