research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
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research Clinical Manifestations of Alopecia in Autoimmune Blistering Diseases: A Cross-Sectional Study
Most patients with autoimmune blistering diseases experienced some hair loss, which may be underreported and linked to disease severity.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Integration of Magnetic Tweezers and Traction Force Microscopy for Exploring the Mechanobiology of Keratinocyte Cell-Cell and Cell-Matrix Anchoring Junctions
The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
research Elevated Expression of Osteopontin Splice Variants in Nonmelanoma Skin Cancer Compared to Normal Skin and Adult Keratinocytes
Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation
Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
research T-Flavanone Improves Male Pattern Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study
t-Flavanone helps improve male pattern hair loss by making hair roots stronger.
research Hair Loss After Terbinafine Treatment
Terbinafine can cause hair loss.
research Alopecia Areata as a Complication of Hair Restoration Surgery
Hair transplant surgery may cause alopecia areata, a new possible complication.
research A Case of Cicatricial Alopecia Associated With Pemphigus: A Case Report
The link between pemphigus and the patient's scarring hair loss is still unclear.
research Pathogenesis and Clinical Features of Alopecia in Epidermolysis Bullosa: A Systematic Review
Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.
research Dermal Fibroblasts Enhance Growth Factors Production by Androgens and Modulate Keratinocyte Proliferation and Differentiation
Androgens increase growth factors in skin cells, which may lead to acne.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Cyclosporin doesn't stop hair loss.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Alopecia as a Rare but Distinct Manifestation of Pemphigus Vulgaris
Hair loss is a rare but recognized symptom of pemphigus vulgaris, with patients usually regrowing hair after treatment.
research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research White Piedra Caused by Trichosporon Inkin: A Report of Two Cases in a Northern Climate
White piedra, a rare fungal infection, was diagnosed in two women in a northern climate.
research Alopecia as a Systemic Disease
Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
research Darier Sign: A Historical Note
Dermatologists diagnose and manage melanoma more effectively than general practitioners.
research Alopecia Triangularis Congenita in Combination with Androgenetic Alopecia
Hair loss improved with treatment and successful transplant.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research A Function for Rac1 in the Terminal Differentiation and Pigmentation of Hair
Rac1 is essential for proper hair structure and color.
research Scalp Involvement in Pemphigus: A Prognostic Marker
Scalp involvement in pemphigus means the disease is more severe and harder to treat.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Patient and Device Generated Variability in Platelet-Derived Growth Factors During Platelet-Rich Plasma Therapy for Hair Loss
Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.
research Imaging Nanoscale Changes in Desmosome Protein Organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.