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This review examined genetic factors in 46, XY differences/disorders of sex development and found that whole-exome sequencing is more effective than panel sequencing for molecular diagnosis. It identified regional genetic variation and emphasized next-generation sequencing's role in detecting variants related to gonadal and androgen-related genes.

This case report describes a 47-year-old patient with scarred alopecia diagnosed as discoid lupus erythematosus, where treatment with multiple medications led to clinical improvement.

This study analyzed research trends in discoid lupus erythematosus, revealing shifting focus areas and highlighted the importance of interdisciplinary collaboration between dermatology and other fields.

This study found that dermoscopy is increasingly accepted among Taiwanese dermatologists, with its use more common among women, younger practitioners, and those with dermoscopy training.

This study found that a single application of TCDD on the skin of hairless mice altered epidermal differentiation, changing keratin expression patterns similarly to a known tumor promoter.

This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.

This case report discusses the diagnostic challenges and management options for three siblings with 46, XY DSD due to type 2 5-α reductase deficiency, highlighting the genetic basis and impact on their quality of life.

This study found that Black patients with discoid lupus erythematosus had significantly worse CLASI damage scores and higher odds for dyspigmentation, scalp involvement, and scarring alopecia compared to non-Black patients.

In this study, researchers used trichoscopy to establish standardized findings for normal hair and scalp characteristics in 360 healthy males, noting significant age-related differences in hair diameter variability and identifying potential pathological indicators like colored dots and scarring not present in healthy individuals.

This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.

Hair shaft malformation contributes to Central Centrifugal Cicatricial Alopecia.

The researchers observed that dermoscopy is valuable for assessing acne scars and their response to treatment, with shorter-duration scars responding more effectively.

This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.

This study found that multiple eccrine duct dilation is highly specific for diagnosing cicatricial alopecia and may indicate scarring processes, aiding in accurate differential diagnosis from noncicatricial alopecias.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.

This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.

This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.

In this case report, researchers describe a 13-year-old phenotypic female with 46,XY karyotype, previously misdiagnosed with androgen insensitivity syndrome, who was later identified to have 17-beta-hydroxysteroid dehydrogenase type 3 deficiency, underscoring the importance of genetic and hormonal tests for accurate diagnosis of sex development disorders.

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.

This review found an increased prevalence of common skin disorders, such as infectious and inflammatory conditions, in patients with Down syndrome and highlighted the need for improved screening and management guidelines.

This study found that digital droplet PCR (ddPCR) outperformed qPCR in detecting replication competent lentivirus in CAR-T products by offering better sensitivity, specificity, and reproducibility, making it a reliable and rapid method for ensuring patient safety.

This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.

This article discusses the factors contributing to acne and reports no new findings, focusing on the role of sebaceous lipids and associated processes.

This study developed a novel multi-scale image descriptor using dictionaries for classifying histological images, achieving average recall and precision measures of 0.81 and 0.86 in identifying specific skin structures and pathologies.

This study reports a novel LC/MS method that separates and analyzes all known ceramide subclasses in human stratum corneum, identifying a new subclass, CER [EOdS], with minimal sample preparation.

D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.

This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.