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Genetic changes in specific proteins contribute to hair loss in some women of African descent.

This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.

Hair shaft changes may be linked to CCCA, but their role is unclear.

This study used electron microscopy to identify a distinct dendritic cell in the human epidermis, similar to the melanocyte, with unique structural features and variable melanin content.

Mutations in the DSG4 gene cause specific hair and scalp issues.

This study developed a synchronized fluorescence spectroscopic approach to quantify finasteride and tadalafil in various forms, achieving high accuracy with %recoveries of about 99.62% and 100.19% respectively, and demonstrated superior environmental friendliness compared to previous methods.

This study found that chromosomal microarray analysis identified copy number variations in 12% of patients with dysmorphic features and congenital anomalies, demonstrating its potential as a diagnostic tool, especially for rare CNVs and immune deficiency linked to the deletion of CTLA4.

This study found that the HS III element in the K14 gene's regulatory sequence promotes gene expression in inner root sheath keratinocytes, highlighting cooperative interactions in keratinocyte-specific gene regulation.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.

This report describes two cases of glucocorticoid resistance syndrome highlighting genetic diversity; one patient improved with low-dose dexamethasone despite negative genetic testing, while the other is monitored with a novel NR3C1 variant.

A deep learning model was developed to help diagnose trichothiodystrophy by analyzing hair patterns.

This article discusses topical and intralesional cidofovir use for SCC and suggests a successful outcome in one case, with no systemic toxicity observed so far.

This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.

This case report describes a 3-year-old boy with trichothiodystrophy, highlighting specific MRI findings of diffuse dysmyelination and osteosclerosis that may be unique to the disorder.

This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.

This study found that suspension culture was more effective than hydrogel-based systems for maintaining spheroid morphology and differentiation of human iPSC-derived definitive endoderm cells.

In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.

This study presents evidence that hair matrix progenitors and the enzyme Stearoyl CoA Desaturase 1 may play a role in maintaining the dermal papilla niche via autocrine Wnt and paracrine Hedgehog signaling in mice.

This study found that dermal papilla cells can induce hair follicle regeneration and maintain growth in vitro and in vivo, with higher ET-1 and SCF expression enhancing this ability.

In this study with a rat muscle defect model, decellularized muscle matrix demonstrated better integration, neovascularization, and myogenesis compared to commercially available acellular dermal matrices, and also showed trends toward reduced inflammation and fibrosis after 30 and 60 days.

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

Various dermatology events and meetings were announced for 1998.

This article reviews the dermabrasion resurfacing technique and details consultation, medication, management practices, and expected outcomes, but it does not present any new clinical data.

This study explored dermatoscopic and histopathologic findings of central centrifugal cicatricial alopecia beyond the vertex scalp, suggesting that dermatoscopy might serve as a less invasive diagnostic tool for subclinical disease.

This study found that the scalp coverage scoring (SCS) method is a non-invasive and reproducible technique that effectively measures hair growth and loss dynamics in male subjects with androgenetic alopecia.

This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.

This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.

This study found that a 3D Matrigel culture technique for dermal papilla cell spheroids can enhance hair follicle inductivity and induce hair-like fiber differentiation in vitro, even with high-passage cells.