research Ginseng in Hair Growth and Viability
Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.
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research The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
research Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression
Lurasidone is effective for bipolar depression and schizophrenia, but more safety data is needed.
research Alopecia Due to Psychotropic Medications
Some psychotropic medications can rarely cause hair loss, and stopping these drugs usually reverses the condition.
research Targeting the Undifferentiated State of Cancer
Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
research Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs
Darker hair in guinea pigs holds more codeine than lighter hair.
research Impaired Prolactin-Lowering Effects of Metformin in Women with Polycystic Ovary Syndrome
Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.
research Blue-Gray Discoloration of the Skin After Levofloxacin Exposure in a 44-Year-Old Man With Pulmonary Tuberculosis
Levofloxacin may cause skin discoloration and hair loss as side effects.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may cause hair loss in rare cases.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Melasma And Other Skin Manifestations Of Oral Contraceptives
Oral contraceptives often cause melasma and other skin issues.
research MAD2B Acts as a Negative Regulatory Partner of TCF4 on Proliferation in Human Dermal Papilla Cells
MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.
research Alopecia Associated with Gabapentin in the Treatment of Neuropathic Pain
Gabapentin may cause hair loss in patients treated for neuropathic pain.
research Delayed Granulomatous Eruption of the Nose Associated with Ruxolitinib
Ruxolitinib can cause a delayed skin reaction on the nose.
research Isotretinoin Treatment Upregulates the Expression of P53 in the Skin and Sebaceous Glands of Patients with Acne Vulgaris
Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
research Effects of Biomaterials Derived from Germinated Hemp Seeds on Stressed Hair Stem Cells and Immune Cells
Hemp seed biomaterials may reduce hair loss and improve hair growth.
research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
The study explored the effects of MT-DADMe-ImmA, an inhibitor of 5′-methylthioadenosine phosphorylase (MTAP), on head and neck cancer cell lines, particularly FaDu and Cal27. The treatment with MT-DADMe-ImmA and 5′-methylthioadenosine (MTA) increased MTA concentrations, decreased polyamines, and induced apoptosis in these cancer cells by causing mitochondrial dysfunction and changes in DNA methylation. The combination treatment was selective for cancer cells, sparing normal fibroblasts and MTAP-deficient breast cancer cells. In a mouse model, MT-DADMe-ImmA led to tumor remission without significant toxicity, suggesting its potential as a selective anticancer agent for tumors sensitive to reduced CpG island methylation.
research Comparison of the Efficacy and Safety of a Picosecond Alexandrite Laser and a Q-Switched Alexandrite Laser for the Treatment of Freckles in Chinese Patients
Both lasers are equally effective and safe for treating freckles.
research Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions
Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
research Hirsutism Following the Use of Bimatoprost Eyedrops for Glaucoma
A woman got unwanted hair growth on her face from using bimatoprost eyedrops for glaucoma.
research Addressing Androgenetic Alopecia: A Complex Disorder with a Multilateral Treatment Strategy
Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
research Prioritizing Susceptibility Genes for the Prognosis of Male-Pattern Baldness With Transcriptome-Wide Association Study
Identified genes linked to male-pattern baldness may help develop new treatments.
research Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus: More Than a Coincidence
The conclusion is that having both Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus may suggest a shared immune response in certain people, and a mix of antimalarial drugs and 5-alfa-reductase inhibitors is recommended for treatment.
research Colchicine in Managing Skin Conditions: A Systematic Review
Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.
research The Application of Optical Technology in the Diagnosis and Therapy of Oxidative Stress-Mediated Hepatic Ischemia-Reperfusion Injury
Optical imaging and light therapy show promise for diagnosing and treating liver injury caused by surgery.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Severe Physical Complications Among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.