research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
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research Cedrol Restricts the Growth of Colorectal Cancer In Vitro and In Vivo by Inducing Cell Cycle Arrest and Caspase-Dependent Apoptotic Cell Death
Cedrol may be an effective treatment for colorectal cancer.
research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia
Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.
research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
research Ethnomedicinal Plants Used by Traditional Healers in the Management of HIV/AIDS Opportunistic Diseases in Rundu, Kavango East Region, Namibia
Traditional healers in Namibia use 70 different plants to treat AIDS-related diseases, and more research is needed to test these plants' effectiveness against HIV.
research Sorafenib Combined with Hepatectomy in Patients with Intermediate-Stage and Advanced Hepatocellular Carcinoma
Sorafenib after liver surgery may increase survival for some liver cancer patients.
research Shushing Down the Epigenetic Landscape Towards Stem Cell Differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research Phase II Evaluation of VDC-1101 in Canine Cutaneous T-Cell Lymphoma
VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.
research Finasteride Delays Atherosclerosis Progression in Mice and Is Associated With a Reduction in Plasma Cholesterol in Men
Finasteride may lower cholesterol and slow heart disease progression.
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research Niosomes as a Promising Carrier for Topical Drug Delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Mitoxantrone
Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
research Differences in Reproductive Toxicology Between Alopecia Drugs: An Analysis on Adverse Events Among Female and Male Cases
Finasteride has a higher risk of reproductive side effects than minoxidil.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research In Vitro Strategies for Mimicking Dynamic Cell–ECM Reciprocity in 3D Culture Models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research Costunolide: A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research Diseases of the Skin: Drug Ill Effects on the Skin
All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.
research Nanotechnology in Dermatology
Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Using MALDI-MSI Analysis to Study Distribution of FOL-005, a Potent, Novel Inhibitor of Human Hair Growth, After Subcutaneous Injection in Mice
FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.
research Cancer Chemotherapy: An Introduction
The book concludes that despite progress, cancer drug treatments have not met the expectations set in the 1960s and 1970s.
research Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Cutaneous Side Effects of Chemotherapy and Radiotherapy
Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
research A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering
Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.
research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Antiandrogen Treatment of Polycystic Ovary Syndrome
Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.
research Anabolic-Androgenic Steroids and Cardiovascular Risk
Using steroids can increase the risk of heart problems.