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Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

The model can effectively test gene functions and drug responses in human skin.

Researchers found three different ways drugs work to treat hair loss from alopecia areata and identified key factors for personalized treatment.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Dermal papilla microtissues could be useful for initial hair growth drug testing.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Neurosteroids show promise for treating epilepsy and more research is needed.

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.

Melanoma thickness at diagnosis is linked to access to dermatologists and preventive services, not to socioeconomic status.

Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.

Living near more dermatologists and using certain cancer screening tests lowers the chance of being diagnosed with advanced skin cancer.

The number of new cases of cutaneous B-cell lymphoma has leveled off since the early 2000s, and survival rates have improved since 1973.

Psoriasis increases annual healthcare costs by $4,044 per patient, with biologic treatments costing significantly more than phototherapy.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Fat under the skin releases HGF which helps hair grow and gain color.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.