research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may cause hair loss in rare cases.
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research Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect
Finasteride helps hair growth but stopping it causes faster hair loss.
research A 6-Month Prospective Study on Efficacy, Safety, and Quality of Life Profiles of Extended-Release Formulation of Valproate in Patients with Epilepsy
Extended-release valproate effectively reduced seizures and improved quality of life in epilepsy patients over 6 months, with some side effects.
research Incidence of Adverse Cutaneous Drug Reactions in a Mexican Sample: An Exploratory Study on Their Association to Tumor Necrosis Factor Alpha TNF2 Allele
Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.
research Intramuscular Corticosteroid Therapy in the Treatment of Alopecia Areata: A Time-to-Event Analysis
Intramuscular corticosteroids are effective and safe for severe alopecia areata, with most patients regrowing hair, but nearly half may relapse.
research Bioequivalence Study of Two Different Coated Tablet Formulations of Finasteride in Healthy Volunteers
Two finasteride tablet types are equally effective and can be swapped.
research Special Focus Issue: Transdermal, Topical, and Follicular Drug Delivery Systems
New drug delivery systems improve treatment effectiveness and patient experience.
research In Vitro Release of Minoxidil From Topical Formulations
Lotions release minoxidil better than creams, with a recommended mix of propylene glycol, water, and ethanol improving effectiveness.
research Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
research Drug Repositioning Approach to Target Viral and Host Cells for COVID-19 Treatment: A Review of In Vivo Experiments and Clinical Studies
Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.
research Drug Information Analysis Service: Effectiveness of Cromolyn Sodium in Treating Asthma in Children Under 2 Years Old
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Skin Lesions in Drug Addicts
Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.
research A Discourse on Human Hair Fibers and Reflections on the Conservation of Drug Molecules
Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Therapeutic Applications of Nanoemulsion-Based Drug Delivery Systems: A Review of Patents in the Last Two Decades
Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
research Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Differential Effects of Propranolol on Heart Rate and Plasma Renin Activity in Patients Treated with Minoxidil
Propranolol affects heart rate and renin levels in minoxidil-treated patients.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research An Update on Drug-Induced Pigmentation
Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
research Drug Eruptions in Dermatology
Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
research Drug-Induced Skin Reactions: A Pathologist's Viewpoint
Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.
research Pharmacokinetics of Two Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism
New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
research Drug Permeation Through Hair Follicles: Importance and Potential
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
research Drug Armamentarium for Alopecia Areata
No cure exists for alopecia areata, and treatments are personalized.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.