Skin Lesions in Drug Addicts

    June 1970 in “ The BMJ
    Dorothy I. Vollum
    Image of study
    TLDR Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.
    In 1970, Dorothy I. Vollum studied 54 drug addicts, aged 16 to 52, over a 12-month period to investigate skin lesions resulting from drug injections. The study revealed that all addicts had scarring at injection sites, 74% had hyperpigmentation, 59% had palpable thrombosed veins, 28% had bruising, and 7% had current abscesses, although 65% had a history of them. Urticaria was observed in two patients and experimentally reproduced in six, while necrotic ulcerating lesions were associated with intravenous barbiturate injections. Histological examination showed foreign body granulomas and carbon particles in the skin of deceased addicts. The study concluded that scarring, hyperpigmentation, thrombosis, and bruising were prevalent among addicts, with barbiturate injections causing particularly severe ulcerations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 18 results

      community Massive preliminary success with my thorough regime

      in Update  4 upvotes 4 years ago
      A 28-year-old male reported significant hair regrowth after 5 weeks using a regime including Minoxidil, Ketozolin shampoo, microneedling, hyaluronic acid, saw palmetto, pumpkin seed, MSM, frankincense, zinc, multivitamins, and vitamin D. He also noted improvements in digestion, dry eyes, and skin health, and observed beard growth from microneedling.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 1 month ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community Started Finasteride almost three months ago and I'm upset

      in Update  153 upvotes 8 months ago
      A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

      community Microneedling makes a difference. Non responders, please read

      in Microneedling  66 upvotes 8 months ago
      A 48-year-old who had been thinning since 25 and reached NW4-5 baldness saw no improvement with 1mg/day finasteride and 5% minoxidil twice a day after 8 months. After copying another person's routine, they now use 0.5mg finasteride, ketoconazole shampoo weekly, daily microneedling with 0.5mm and 1mm once a week, and apply minoxidil twice daily, resulting in baby hairs on their bald spot and temples after three months.

      community Almost 8 months. 40 years old. Owe it all to this sub.

      in Progress Pictures  815 upvotes 1 year ago
      A 40-year-old man successfully regrew his hair in 8 months using 0.5mg Dutasteride, 2.5 oral minoxidil, minoxidil foam twice a day, derma rolling/stamping twice a week, and retinol serum. The community praised his progress, asked about his routine, and shared their own experiences.

    Similar Research

    5 / 1000+ results
      Atlas of Geriatric Dermatology

      research Atlas of Geriatric Dermatology

      2 citations, January 2014 in “Springer eBooks”
      The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
      Cutaneous Drug Reactions

      research Cutaneous Drug Reactions

      1 citations, January 2010 in “Elsevier eBooks”
      Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
      Acne and Acneiform Eruptions

      research Acne and Acneiform Eruptions

      2 citations, January 2011 in “Elsevier eBooks”
      Early treatment of acne is crucial to prevent scarring and psychological effects.
      Complications in Aesthetic Surgery

      research Complications in Aesthetic Surgery

      August 2016 in “InTech eBooks”
      Esthetic surgery complications can include infections, nerve injury, and more; proper evaluation and technique help prevent them.