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Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

Redefining drug dosages is crucial when repurposing them for new uses.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

Transethosomes improve drug delivery through the skin by overcoming the outer skin layer's barrier.

Tadalafil and Finasteride may help treat aggressive melanoma.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

The model and estimator can predict drug exposure in kidney transplant patients well.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

A cat's hyperactivity and hair loss were caused by eating valproic acid but improved after stopping access to the drug.

New materials help control stem cell growth and specialization for medical applications.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Innovative methods are reducing animal testing and improving biomedical research.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Finasteride effectively treats male hair loss, improving growth and density.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.