research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
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research Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins
Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges
Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Hair Versus Nails: Is There a Place for Other Keratin Matrices?
Nails are a useful alternative to hair for analyzing long-term substance exposure.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research On the Use of Micro-Imager to Directly Visualize Drug Distribution in Human Skin
Micro-Imager® helps see how drugs spread in human skin.
research Tackling Polycystic Ovary Syndrome
The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.
research Clinico-Etiological and Histopathological Correlation in Erythroderma: In a Tertiary Care Hospital of Eastern Odisha
Psoriasis is the most common cause of erythroderma, and proper medical follow-up is crucial.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Hyperbranched Glycerol-Based Core-Amphiphilic Branched Shell Nanotransporters for Dermal Drug Delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Preparation, Optimization, In Vitro Evaluation and Ex Vivo Permeation Studies of Finasteride Loaded Gel Formulations Prepared Using Response Surface Methodology
The combination of propylene glycol and Tween® 80 improves finasteride gel effectiveness.
research Viva Questions from the Indian Journal of Dermatology, Venereology, and Leprology
The document concludes that various skin conditions have specific characteristics and treatments, and highlights the importance of vitamin D in managing these dermatological issues.
research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Reduction of Diameter of Hair Shaft Among Women With Hirsutism
Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
research Ethosome as a Potential Transdermal Drug Delivery System
Ethosomes are a promising way to deliver drugs through the skin.
research Nanostructured Drug Delivery Systems for Targeting 5-Alpha-Reductase Inhibitors to the Hair Follicle
Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.
research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
research Poria Cocos Polysaccharides Attenuate Chronic Nonbacterial Prostatitis by Targeting the Gut Microbiota: Comparative Study of Poria Cocos Polysaccharides and Finasteride in Treating Chronic Prostatitis
Poria cocos polysaccharides and finasteride both help treat chronic nonbacterial prostatitis, but Poria cocos polysaccharides also improve gut health.
research Old Drug New Indication: Tofacitinib for a New Crop of Hair?
Tofacitinib might be used to treat hair loss.
research Assessment of Prescribing Information for Generic Drugs Manufactured in the Middle East and Marketed in Saudi Arabia
Generic drug inserts in Saudi Arabia often have inaccurate information, needing better regulation and quality control.
research Unraveling Childhood Tinea Capitis: A Multi-Dimensional Investigation Using Dermoscopy, Scanning Electron Microscopy, and Mass Spectrometry
Tinea capitis in a child was caused by a fungus from cats, highlighting the need for accurate diagnosis and treatment.
research TMPRSS2, Required for SARS-CoV-2 Entry, Is Downregulated in Lung Cells by Enzalutamide, a Prostate Cancer Therapeutic
A prostate cancer drug can lower the levels of a protein that the coronavirus uses to enter lung cells.
research Efficacy of CD101, a Novel Echinocandin, in the Treatment of Dermatophytosis Using a Guinea Pig Model
CD101 is highly effective in treating dermatophytosis in guinea pigs.
research Hair Regenerative Effect of Silk Fibroin Hydrogel with Incorporation of FGF-2-Liposome and Its Potential Mechanism in Mice with Testosterone-Induced Alopecia Areata
The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research Letter to the Editor: Androgenetic Alopecia; Drug Safety and Therapeutic Strategies
Dutasteride is a safe and effective treatment for hair loss.
research Ketoconazole: A Promising Drug for Fungal Infections
Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.
research Risk of Rhabdomyolysis from 5-Alpha Reductase Inhibitors
Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.